60758-79-4

Basic information

• Product Name: 3-ETHOXY-4-HYDROXYBENZONITRILE
• Synonyms: Benzonitrile, 3-ethoxy-4-hydroxy-
• CAS NO: 60758-79-4
• Molecular Formula: C₉H₉NO₂
• Molecular Weight: 163.17
• Mol File: 60758-79-4.mol
• Article Data: 6

Chemical Properties

• Melting Point: 66 °C
• Boiling Point: 303.1°C at 760 mmHg
• Flash Point: 137.1°C
• Appearance: /
• Density: 1.19g/cm³
• Vapor Pressure: 0.000529mmHg at 25°C
• Refractive Index: 1.556
• PKA: 7.97±0.18(Predicted)
• CAS DataBase Reference: 3-ETHOXY-4-HYDROXYBENZONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-ETHOXY-4-HYDROXYBENZONITRILE(60758-79-4)
• EPA Substance Registry System: 3-ETHOXY-4-HYDROXYBENZONITRILE(60758-79-4)

Safety Data

• Hazardous Substances Data: 60758-79-4(Hazardous Substances Data)

Usage

General Description

3-Ethoxy-4-hydroxybenzonitrile is a chemical compound with the molecular formula C9H9NO2. It is a white solid at room temperature, and it is commonly used in the pharmaceutical industry as an intermediate for the synthesis of various drugs and pharmaceutical products. 3-ETHOXY-4-HYDROXYBENZONITRILE is known for its aromatic and hydroxyl properties, as well as its nitrile group, which makes it suitable for use in drug development. Additionally, 3-ethoxy-4-hydroxybenzonitrile is also used in organic synthesis and research, where its unique chemical structure and properties make it a valuable and versatile compound for various applications.

InChI:InChI=1/C9H9NO2/c1-2-12-9-5-7(6-10)3-4-8(9)11/h3-5,11H,2H2,1H3

Upstream product

• 121-32-4 4-hydroxy-3-ethoxybenzaldehyde 
• 34184-93-5 3-ethoxy-4-hydroxybenzaldoxime 
• 5438-50-6 4-acetoxy-3-ethoxy-benzonitrile 

Downstream Products

• 60758-86-3 3-ethoxy-4-methoxybenzenecarbonitrile 
• 1450657-31-4 1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethen-1-amine 
• 608141-42-0 (S)-2-[1 (3-ethoxy-4-methoxyphenyl)]-1-methanesulfonyl-2-ethylamine 
• 608142-27-4 (R)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)-ethylamine 
• 17183-38-9 1-(3-ethoxy-4-hydroxyphenyl)pentan-1-one 

Relevant articles and documents

IMPROVED PROCESS FOR THE PREPARATION OF APREMILAST

The present invention relates to an improved process for the preparation of Apremilast of formula (I).

PERFUME SYSTEMS

The present application relates to perfume raw materials, perfume delivery systems and consumer products comprising such perfume raw materials and/or such perfume delivery systems, as well as processes for making and using such perfume raw materials, perfume delivery systems and consumer products. Such perfume raw materials and compositions, including the delivery systems, disclosed herein expand the perfume communities' options as such perfume raw materials can provide variations on character and such compositions can provide desired odor profiles.

Solvent free, microwave assisted conversion of aldehydes into nitriles and oximes in the presence of NH2OH · HCl and TiO2

Aromatic aldehydes bearing electron-donating groups are easily converted into their respective nitriles using NH2OH · HCl and TiO 2 under microwave irradiation, while those bearing an electron-withdrawing group give the corresponding oximes.