60759-10-6

Basic information

• Product Name: CHEMBRDG-BB 4010333
• Synonyms: CHEMBRDG-BB 4010333;4-(1,3-THIAZOL-4-YL)ANILINE;4-(1,3-thiazol-4-yl)aniline(SALTDATA: FREE)
• CAS NO: 60759-10-6
• Molecular Formula: C₉H₈N₂S
• Molecular Weight: 176.24
• Mol File: 60759-10-6.mol
• Article Data: 4

Chemical Properties

• Melting Point: 99 °C
• Boiling Point: 347.414°C at 760 mmHg
• Flash Point: 163.91°C
• Appearance: /
• Density: 1.262g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.66
• PKA: 3.24±0.10(Predicted)
• CAS DataBase Reference: CHEMBRDG-BB 4010333(CAS DataBase Reference)
• NIST Chemistry Reference: CHEMBRDG-BB 4010333(60759-10-6)
• EPA Substance Registry System: CHEMBRDG-BB 4010333(60759-10-6)

Safety Data

• Hazard Codes: Xi
• Statements: 41
• Safety Statements: 26-39
• RIDADR: UN 2811 6.1 / PGIII
• Hazardous Substances Data: 60759-10-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C9H8N2S/c10-8-3-1-7(2-4-8)9-5-12-6-11-9/h1-6H,10H2

Upstream product

• 53101-04-5 ethyl 4-(4-nitrophenyl)-1,3-thiazole-2-carboxylate 
• 99-81-0 4-Nitrophenacyl bromide 
• 532-27-4 1-chloroacetophenone 
• 115-08-2 thiocarboxamide 
• 2631-71-2 4-aminophenacyl chloride 
• 3704-42-5 4-(4-nitro-phenyl)-thiazole 

Downstream Products

• 1381761-44-9 C₂₇H₃₃N₉O₄S 
• 1381761-45-0 C₂₄H₂₉N₉O₄S 
• 7091-88-5 1-(4-pentyloxy-phenyl)-3-(4-thiazol-4-yl-phenyl)-thiourea 
• 7021-76-3 1-(4-butoxy-phenyl)-3-(4-thiazol-4-yl-phenyl)-thiourea 
• 7021-77-4 1-(4-isobutoxy-phenyl)-3-(4-thiazol-4-yl-phenyl)-thiourea 
• 7021-74-1 1-(4-propoxy-phenyl)-3-(4-thiazol-4-yl-phenyl)-thiourea 
• 7188-41-2 1-(4-ethoxy-phenyl)-3-(4-thiazol-4-yl-phenyl)-thiourea 
• 7021-73-0 1-(4-methoxy-phenyl)-3-(4-thiazol-4-yl-phenyl)-thiourea 
• 95426-28-1 N-{4-[bis-(2-chloro-ethyl)-amino]-benzylidene}-4-thiazol-4-yl-aniline 
• 7021-75-2 1-(4-isopropoxy-phenyl)-3-(4-thiazol-4-yl-phenyl)-thiourea 
• 25020-92-2 1,3-bis-(4-thiazol-4-yl-phenyl)-thiourea 

Relevant articles and documents

MODULATORS OF HISTONE METHYLTRANSFERASE, AND METHODS OF USE THEREOF

Disclosed are compounds, pharmaceutical compositions containing the compounds, and the uses of the compounds and compositions as modulators of histone methyltransferases, and for treating diseases influenced by modulation of histone methyltransferase activity.

NOVEL AMIDE COMPOUNDS

A compound of the formula (I):R1-A-X-NHCO-Y-R2 ???whereinR1 is heterocyclic group which may have suitable substituents, or phenyl which may have suitable substituents,R2 is condensed phenyl which may have suitable substituents, phenyl which may have suitable substituents, or thienyl which may have suitable substituents,A is a group of the formula:-(CH2)t-(O)m- or in which R3 and R4 are each hydrogen or linked together to form imino,R5 is hydrogen or lower alkyl,t is 0, 1 or 2,p, m and n are each 0 or 1,X is phenylene which may have suitable substituents, or bivalent heterocyclic group containing nitrogen which may have suitable substituents,Y is bond, lower alkylene, or lower alkenylene, and a salt thereof.