6082-22-0

Basic information

• Product Name: O-Methyl-N-acetyl-2-deoxy-a-D-galactosamine
• Synonyms: O-Methyl-N-acetyl-2-deoxy-α-D-galactosamine;1-O-Methyl-N-acetyl-α-D-galactosamine;Methyl 2-(acetylamino)-2-deoxy-α-D-galacto-hexopyranoside;Methyl α-N-acetyl galactosamine;Me-αGalNAc;Me-α-GalNAc;N-Acetyl-1-O-methyl-α-D-galactosamine;Methyl N-acetyl-2-deoxy-α-D-galactosaMine
• CAS NO: 6082-22-0
• Molecular Formula: C₉H₁₇NO₆
• Molecular Weight: 235.23438
• Product Categories: 13C & 2H Sugars;Carbohydrates & Derivatives
• Mol File: 6082-22-0.mol
• Article Data: 28

Chemical Properties

• Melting Point: 217-219°C
• Boiling Point: 525.5±50.0 °C(Predicted)
• Appearance: /
• Density: 1.36±0.1 g/cm3(Predicted)
• Storage Temp.: -20°C Freezer
• Solubility: Methanol (Slightly), Water (Slightly)
• PKA: 12.98±0.70(Predicted)
• Stability: Hygroscopic
• CAS DataBase Reference: O-Methyl-N-acetyl-2-deoxy-a-D-galactosamine(CAS DataBase Reference)
• NIST Chemistry Reference: O-Methyl-N-acetyl-2-deoxy-a-D-galactosamine(6082-22-0)
• EPA Substance Registry System: O-Methyl-N-acetyl-2-deoxy-a-D-galactosamine(6082-22-0)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 6082-22-0(Hazardous Substances Data)

Usage

Description

O-Methyl-N-acetyl-2-deoxy-a-D-galactosamine is a modified carbohydrate molecule derived from the naturally occurring sugar, 2-deoxy-a-D-galactose. It features a methyl group attached to the oxygen atom and an acetyl group attached to the nitrogen atom, which distinguishes it from its parent compound. This modification may confer unique properties and potential applications in various fields.

Uses

Used in Medical Research:
O-Methyl-N-acetyl-2-deoxy-a-D-galactosamine is used as a molecular probe for the detection of epiglycanin-related glycoproteins in body fluids of cancer patients. This application is significant because the presence of these glycoproteins can be indicative of certain types of cancer, and their detection can aid in diagnosis and monitoring of the disease.
Used in Diagnostics:
In the diagnostics industry, O-Methyl-N-acetyl-2-deoxy-a-D-galactosamine can be utilized as a component in the development of antibody-based assays. These assays can help in the identification and quantification of specific glycoproteins, which may be crucial for understanding the progression of cancer and the effectiveness of treatments.
Used in Drug Development:
O-Methyl-N-acetyl-2-deoxy-a-D-galactosamine may also have potential applications in drug development, particularly in the design of targeted therapies for cancer. The unique structural features of this molecule could be exploited to enhance the specificity and efficacy of drugs that interact with glycoproteins implicated in cancer progression.
Used in Biochemical Analysis:
In the field of biochemistry, O-Methyl-N-acetyl-2-deoxy-a-D-galactosamine can be employed as a reference compound or standard for the analysis of glycoproteins and their interactions with other biomolecules. This can be valuable for understanding the complex roles that glycoproteins play in various biological processes, including those related to cancer.

Upstream product

• 67-56-1 methanol 
• 7512-17-6 N-Acetyl-D-glucosamine 
• 72-87-7 N-acetyl-D-glucosamine 
• 1078691-95-8 (+)-D-glucosamine hydrochloride 
• 75-36-5 acetyl chloride 
• 10036-64-3 N-acetyl-D-glucosamine 
• 72-87-7 N-acetyl-D-galactosamine 
• 23646-68-6 4-nitrophenyl 2-acetamido-2-deoxy-α-D-galactopyranoside 
• 6082-04-8 methyl 2-acetylamido-2-deoxy-D-glucoside 
• 83071-89-0 methyl 2-acetamido-2-deoxy-α-D-xylo-hexopyranosid-4-ulose O-methyloxime 
• 114066-50-1 sarasinoside B₁ 
• 10385-50-9 2-acetamido-1,3,4,6-tetra-O-acetyl-2-deoxy-α-D-galactopyranoside 
• 3006-60-8 2-acetamido-1,3,4,6-tetra-O-acetyl-2-deoxy-β-D-galactopyranose 

Downstream Products

• 375824-36-5 methyl 2-acetamido-2-deoxy-6-O-p-tolylsulfonyl-β-D-glucopyranoside 
• 53756-24-4 ((2R,3S,4R,5R,6S)-5-acetamido-3,4-dihydroxy-6-methoxytetrahydro-2H-pyran-2-yl)methyl 4-methylbenzenesulfonate 
• 75669-79-3 methyl 2-acetamido-2-deoxy-3-O-(β-D-galactopyranosyl)-α-D-galactopyranoside 
• 87038-18-4 methyl 2-acetylamido-4,6-O-benzylidene-2-deoxy-β-D-glucopyranoside 
• 6619-02-9 methyl N-acetyl-2-amino-4,6-O-benzylidene-2-deoxy-α-D-glucopyranoside 
• 188666-34-4 methyl 2-acetamido-2-deoxy-4,6-O-(p-methoxybenzylidene)-α-D-galactopyranoside 
• 176691-02-4 methyl 2-acetamido-3,6-di-O-benzoyl-2-deoxy-α-D-galactopyranoside 
• 87171-50-4 methyl 2-acetamido-3,4,6-tri-O-(p-bromobenzoyl)-2-deoxy-α-D-galactopyranoside 
• 17296-10-5 methyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-α-D-galacto-pyranoside 
• 42756-57-0 methyl 2-acetamido-2-deoxy-6-O-trityl-D-glucopyranoside 
• 3006-60-8 Acetic acid (2R,3R,4R,5S,6R)-2,5-diacetoxy-6-acetoxymethyl-3-acetylamino-tetrahydro-pyran-4-yl ester 
• 2771-48-4 methyl 2-acetamido-3,4,6-O-triacetyl-2-deoxy-β-D-glucopyranoside 
• 2595-39-3 methyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-α-D-glucopyranoside 
• 88295-36-7 1-O-Methyl-2-N-acetylamino-2-deoxy-4,6-O-benzyliden-α,β-D-glucopyranosid 

Relevant articles and documents

Design, physico-chemical characterization andin vitrobiological activity of organogold(iii) glycoconjugates

To develop new metal-based glycoconjugates as potential anticancer agents, four organometallic gold(iii)-dithiocarbamato glycoconjugates of the type [AuIII(2-Bnpy)(SSC-Inp-GlcN)](PF6) (2-Bnpy: 2-benzylpyridine; Inp: isonipecotic moie

Ultrasonication-Assisted Synthesis of a d-Glucosamine-Based β-CD Inclusion Complex and Its Application as an Aqueous Heterogeneous Organocatalytic System

For the first time, an inclusion complex has been crafted between a carbohydrate-based molecule and a β-cyclodextrin (CD) hydrophobic cavity for asymmetric catalytic applications. This novel d-glucosamine-based inclusion compound has been synthesized in h

Selective anomeric acetylation of unprotected sugars in water

High yielding selective acetylation of only the anomeric hydroxyl of unprotected sugars is possible in aqueous solution using 2-chloro-1,3-dimethylimidazolinium chloride (DMC), thioacetic acid, and a suitable base. The reaction, which may be performed on a multi-gram scale, is stereoselective for sugars that possess a hydroxyl group at position-2, exclusively yielding the 1,2-trans products. The use of an iterative reagent addition procedure allows the use of sodium carbonate as the base, avoiding the formation of triethylammonium salts, which may hamper product purification. The glycosyl acetate products may be used as donor substrates for glycosidase-catalysed synthesis. The crude aqueous acetylation reaction mixture may also be used for this purpose.