608515-45-3Relevant articles and documents
A new and facile approach to 1,2-dihydroisoquinolin-3(4: H)-imines by the Cu(i)-catalyzed reaction of 2-ethynylbenzyl methanesulfonates, sulfonyl azides and amines
Huang, Ying,Yi, Weiyin,Sun, Qihui,Zhang, Lirong,Yi, Fengping
, p. 74 - 79 (2018)
A new, step-economical and operationally simple access to unsubstituted 1,2-dihydroisoquinolin-3(4H)-imines by Cu-catalyzed MCRs under mild conditions is described. In addition, selective hydrolysis of imines to the corresponding 1,2-dihydroisoquinolin-3(4H)-ones under refluxed conc. HCl has also been investigated.
Catalytic Asymmetric Tandem Cycloisomerization/[5+2] Cycloaddition Reaction of N-Aryl Nitrone Alkynes with Methyleneindolinones
Hu, Bowen,Zhang, Xiying,Mo, Yuhao,Li, Jinzhao,Lin, Lili,Liu, Xiaohua,Feng, Xiaoming
supporting information, p. 1034 - 1039 (2020/02/04)
An asymmetric tandem cycloisomerization and intermolecular [5+2] cycloaddition reaction of 2-ethynylphenyl-substituted nitrones with methyleneindolinones was realized. The process includes the palladium(II)-promoted in situ formation of azomethine ylide and the following chiral N,N′-dioxide-Co(II) complex-catalyzed regio-, diastereo-, and enantioselective [5+2] cycloaddition reaction. The desired spiro-tropanyl oxindoles were obtained in good yields with excellent dr and ee values. On the basis of the determination of the catalyst structure, a possible transition state model was proposed.
Chiral Cyclometalated Oxazoline Gold(III) Complex-Catalyzed Asymmetric Carboalkoxylation of Alkynes
Jiang, Jia-Jun,Cui, Jian-Fang,Yang, Bin,Ning, Yulu,Lai, Nathanael Chun-Him,Wong, Man-Kin
supporting information, p. 6289 - 6294 (2019/08/26)
Asymmetric catalysis by using novel chiral O,O′-chelated 4,4′-biphenol cyclometalated oxazoline gold(III) complexes has been developed. A high yield (≤89%) and a high enantioselectivity (≤90% ee) were achieved in asymmetric carboalkoxylation of alkynes. E
