6102-38-1

Basic information

• Product Name: N-{4-[(4-methylpyrimidin-2-yl)sulfamoyl]phenyl}-4-nitrobenzenesulfonamide
• Synonyms: benzenesulfonamide, N-[4-[[(4-methyl-2-pyrimidinyl)amino]sulfonyl]phenyl]-4-nitro-
• CAS NO: 6102-38-1
• Molecular Formula: C₁₁H₁₈O
• Molecular Weight: 449.4609
• Mol File: 6102-38-1.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 700.9°C at 760 mmHg
• Flash Point: 377.7°C
• Density: 1.592g/cm³
• Vapor Pressure: 1.7E-19mmHg at 25°C
• Refractive Index: 1.685
• CAS DataBase Reference: N-{4-[(4-methylpyrimidin-2-yl)sulfamoyl]phenyl}-4-nitrobenzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-{4-[(4-methylpyrimidin-2-yl)sulfamoyl]phenyl}-4-nitrobenzenesulfonamide(6102-38-1)
• EPA Substance Registry System: N-{4-[(4-methylpyrimidin-2-yl)sulfamoyl]phenyl}-4-nitrobenzenesulfonamide(6102-38-1)

Safety Data

• Hazardous Substances Data: 6102-38-1(Hazardous Substances Data)

Upstream product

• 32042-78-7 acetic acid (1S*,8aS*)-(+/-)-8a-methyl-6-oxo-1,2,3,4,6,7,8,8a-octahydronaphthalen-1-yl ester 
• 65083-11-6 (+/-) (1α,6α,8aα)-1,2,3,4,6,7,8,8a-octahydro-8a-methyl-1,6-naphthalenediol 
• 18317-97-0 rac.-1β-Acetoxy-9β-methyl-Δ⁵-trans-oktalin 
• 1655-07-8 ethyl 2-oxocyclohexane carboxylate 
• 29474-11-1 (2-methylcyclohex-1-en-1yl)methanol 
• 80845-00-7 cis-9-methyl-1-decalone 
• 6102-33-6 (+/-)-8a-Methyl-(4ar,8at)-decahydro-[1t]naphthol 
• 18631-96-4 3,4,5,6,7,8-hexahydro-2H-naphthalen-1-one 
• 74-88-4 methyl iodide 
• 71268-55-8 9-phenylthiomethyl-1-decalone 
• 78828-14-5 methyl-1 ethylenedioxy-2,2 bicyclo(4.4.0)decane trans 
• 124664-61-5 1-allyl-2-methyl-cyclohexene 
• 54482-61-0 (+/-)-2-((Ξ)-furfurylidene)-8a-methyl-(4ar,8at)-octahydro-naphthalen-1-one 
• 6102-33-6 (+/-)-8a-Methyl-(4ar,8at)-decahydro-[1c]naphthol 

Downstream Products

• 120174-15-4 (3aα,5aβ,9aα,9bα)-3a,4,5,5a,6,7,8,9,9a-decahydro-9a,9b-dimethyl-2-(phenylamino)-1H-benzinden-1-one 
• 120174-16-5 (3aα,5aβ,9aα,9bα)-dodecahydro-9a,9b-dimethyl-2-(phenylamino)-1H-benzinden-1-one 
• 120174-12-1 2-(2-aminophenyl)dodecahydro-9a,9b-dimethyl-2-(methylthio)-1H-benzinden-1-one 
• 54482-61-0 (+/-)-2-((Ξ)-furfurylidene)-8a-methyl-(4ar,8at)-octahydro-naphthalen-1-one 

Relevant articles and documents

Regiodivergent Remote Arylation of Cycloalkanols to Dysideanone′s Fused Carbotetracycles and Its Bridged Isomers

Regiodivergent γ and γ′ arylations across an all-carbon quaternary center of cycloalkanols to access enantioenriched fused and bridged carbotetracycles are reported. The conformation of the carbocation guided either sequential stereospecific β-C-Me/γ-C?H-shifts or β-C-Me/γ′-C?H-shifts, providing fused carbotetracyclic analogs of dysideanone or bridged tetracycles, respectively. The reaction is highly stereoselective in building three contiguous stereocenters, where one, two, or three could be all-carbon quaternary centers. Interestingly, mechanistic studies revealed a crucial role of a methyl substituent in controlling regioselectivity.

Preparative Bioorganic Chemistry, XVII. Reduction of a Prochiral Diketone, 9-Methyl-trans-decalin-1,8-dione, with Baker's Yeast

Reduction of 9-methyl-trans-decalin-1,8-dione (1) with baker's yeast affords (8S,9R,10R)-8-hydroxy-9-methyl-trans-1-decalone (8) as the major product in 47percent yield.Its (8S,9S,10S)-isomer (9, 14percent yield) and (1S,8S)-9-methyl-trans-1,8-diol (10, 7percent yield) are obtained as minor products.Baker's yeast cannot reduce 9-methyl-cis-decalin-1,8-dione (2). Key Words: Asymmetric reduction / Baker's yeast / Yeast / Saccharomyces cerevisia / Enzymes / trans-1-Decalone derivatives / trans-1,8-Decalindione derivatives