61040-98-0Relevant articles and documents
A General and Practical Approach for the Synthesis of 1,2,4-Trioxanes Catalyzed by Silica-Ferric Chloride
Zhang, Mo,Han, Yi,Niu, Jia-Liang,Zhang, Zhan-Hui
, p. 3618 - 3625 (2017/09/13)
An efficient and practical method has been developed for the facile synthesis of 1,2,4-trioxanes by the condensation of β-hydroperoxy alcohols and carbonyl compounds in the presence of a catalytic amount of silica-supported ferric chloride (FeCl3/SiO2) at room temperature. The method has the benefits of operational simplicity, high yields and potential large-scale application. Moreover, the catalyst can be readily recovered by simple filtration and reused up to five times while almost maintaining its catalytic activity. (Figure presented.).