61077-69-8

Basic information

• Product Name: Benzeneethanol, a-[(trimethylsilyl)ethynyl]-
• Synonyms: 4-(trimethylsilyl)-1-phenylbut-3-yn-2-ol
• CAS NO: 61077-69-8
• Molecular Formula: C13H18OSi
• Molecular Weight: 218.371
• Mol File: 61077-69-8.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 304.0±30.0 °C(Predicted)
• Density: 0.984±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Benzeneethanol, a-[(trimethylsilyl)ethynyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneethanol, a-[(trimethylsilyl)ethynyl]-(61077-69-8)
• EPA Substance Registry System: Benzeneethanol, a-[(trimethylsilyl)ethynyl]-(61077-69-8)

Safety Data

• Hazardous Substances Data: 61077-69-8(Hazardous Substances Data)

Upstream product

• 122-78-1 phenylacetaldehyde 
• 1066-54-2 trimethylsilylacetylene 
• 107383-25-5 (3-benzyloxy-prop-1-ynyl)trimethylsilanebenzyl ether 
• 54655-07-1 lithium trimethylsilylacetylenide 
• 14630-40-1 Bis(trimethylsilyl)ethyne 

Downstream Products

• 88768-84-7 1-phenyl-4-trimethylsilylbutane-3-yn-2-one 
• 1433991-85-5 C₂₆H₂₄N₂O₂S 
• 1433993-17-9 3-benzyl-2,3,4,5-tetrahydro-1H-benzo[c]azepine 
• 1433993-16-8 4-(2-(bromomethyl)phenyl)-1-phenylbutan-2-amine trifluoroacetate 
• 1433993-14-6 tert-butyl (4-(2-(bromomethyl)phenyl)-1-phenylbutan-2-yl)carbamate 
• 1433993-13-5 tert-butyl (4-(2-(hydroxymethyl)phenyl)-1-phenylbutan-2-yl)carbamate 
• 1433993-12-4 methyl 2-(3-((tert-butoxycarbonyl)amino)-4-phenylbutyl)benzoate 
• 1433993-11-3 methyl 2-(3-amino-4-phenylbutyl)benzoate 
• 1433993-10-2 methyl 2-(3-azido-4-phenylbutyl)benzoate 
• 1433993-09-9 methyl 2-(3-((methylsulfonyl)oxy)-4-phenylbutyl)benzoate 
• 1433993-08-8 methyl 2-(3-hydroxy-4-phenylbutyl)benzoate 
• 1433993-07-7 methyl 2-(3-hydroxy-4-phenylbut-1-yn-1-yl)benzoate 
• 1284300-20-4 (3-(allyloxy)-4-phenylbut-1-ynyl)trimethylsilane 
• 1284299-78-0 C₁₆H₂₂O₂Si 

Relevant articles and documents

Enantioselective Inverse Electron Demand (3 + 2) Cycloaddition of Palladium-Oxyallyl Enabled by a Hydrogen-Bond-Donating Ligand

Cycloaddition reactions between oxyallyl cations and alkenes are important transformations for the construction of ring systems. Although (4 + 3) cycloaddition reactions of oxyallyl cations are well-developed, (3 + 2) cycloadditions remain rare, and an as

Silver(I)-catalyzed reaction between pyrazole and propargyl acetates: Stereoselective synthesis of the scorpionate ligands (E)-allyl-gem-dipyrazoles (ADPs)

The reaction between readily accessible pyrazole and propargyl acetates in the presence of Ag(I) catalyst yielded a new class of (E)-allyl-gem-dipyrazole scorpionate ligands: 1-aryl-2-N-pyrazolyl allyl acetates and 1,3-dipyrazolyl-3-arylpropene. The reaction showed broad substrate scope, and various functional and protecting groups were tolerated under the reaction conditions. The palladium(II) scorpionate complex could thus be easily prepared and successfully employed in Suzuki-Miyaura cross-couplings in water.

Gold-catalysed activation of epoxides: Application in the synthesis of bicyclic ketals

Gold-catalysed generation of diol equivalents from epoxides and their intramolecular reaction with Ca≡C bonds to generate bicyclic ketals is presented. This reaction essentially involves the formation of an acetonide, which subsequently cyclises on the alkyne intramolecularly under gold catalysis conditions. This method could be extended to make optically pure bicyclic ketals. Deuterium incorporation experiments were carried out to ascertain the mechanism of the reaction. Sequential activation of epoxide and alkyne moieties by a gold catalyst in acetone as solvent has been achieved. This strategyhas been employed to synthesise bicyclic ketals from epoxy alkynes. Copyright