61085-36-7 Usage
Description
4-Piperidinecarbonitrile, 4-(phenylamino)-1-(2-phenylethyl)is a chemical compound with the molecular formula C20H22N4. It is a derivative of piperidine and contains a nitrile group and a phenylamino group. 4-Piperidinecarbonitrile, 4-(phenylamino)-1-(2-phenylethyl)is characterized by its unique structure and properties, making it a valuable intermediate in organic chemistry and chemical research.
Uses
Used in Pharmaceutical Industry:
4-Piperidinecarbonitrile, 4-(phenylamino)-1-(2-phenylethyl)is used as a building block in the synthesis of various biologically active molecules for pharmaceutical applications. Its unique chemical structure allows for the development of compounds with diverse therapeutic effects.
Used in Agrochemical Industry:
4-Piperidinecarbonitrile, 4-(phenylamino)-1-(2-phenylethyl)is also utilized in the production of agrochemicals, where it serves as an important intermediate in the synthesis of various agrochemical products. Its properties and structure contribute to the development of effective and targeted agrochemicals.
Used in Organic Synthesis:
4-Piperidinecarbonitrile, 4-(phenylamino)-1-(2-phenylethyl)is used as a versatile building block in organic synthesis for the preparation of a wide range of compounds with diverse applications. Its unique structure and properties make it suitable for the synthesis of various organic compounds, contributing to the advancement of chemical research and development.
Check Digit Verification of cas no
The CAS Registry Mumber 61085-36-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,1,0,8 and 5 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 61085-36:
(7*6)+(6*1)+(5*0)+(4*8)+(3*5)+(2*3)+(1*6)=107
107 % 10 = 7
So 61085-36-7 is a valid CAS Registry Number.
61085-36-7Relevant articles and documents
Nonpeptide small molecule agonist and antagonist original leads for neuropeptide FF1 and FF2 receptors
Journigan, V. Blair,Mésangeau, Christophe,Vyas, Neha,Eans, Shainnel O.,Cutler, Stephen J.,McLaughlin, Jay P.,Mollereau, Catherine,McCurdy, Christopher R.
, p. 8903 - 8927 (2015/03/14)
Neuropeptide FF1 and FF2 receptors (NPFF1-R and NPFF2-R), and their endogenous ligand NPFF, are one of only several systems responsible for mediating opioid-induced hyperalgesia, tolerance, and dependence. Currently, no small molecules displaying good affinity or selectivity for either subtype have been reported, to decipher the role of NPFF2-R as it relates to opioid-mediated analgesia, for further exploration of NPFF1-R, or for medication development for either subtype. We report the first nonpeptide small molecule scaffold for NPFF1,2-R, the guanidino-piperidines, and SAR studies resulting in the discovery of a NPFF1 agonist (7b, Ki = 487 ± 117 nM), a NPFF1 antagonist (46, Ki = 81 ± 17 nM), and a NPFF2 partial antagonist (53a, Ki = 30 ± 5 nM), which serve as leads for the development of pharmacological probes and potential therapeutic agents. Testing of 46 alone was without effect in the mouse 48 °C warm-water tail-withdrawal test, but pretreatment with 46 prevented NPFF-induced hyperalgesia.
N-(4-piperidinyl)-N-phenylamides
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, (2008/06/13)
Novel N-(4-piperidinyl)-N-phenylamides and -carbamates having very potent analgesic activity, methods of preparing same and useful intermediates therefor.
