61086-18-8

Basic information

• Product Name: N-[4-(methoxymethyl)piperidin-4-yl]-N-phenylpropionamide
• Synonyms: N-[4-(methoxymethyl)piperidin-4-yl]-N-phenylpropionamide;noralfentanil;N-[4-(Methoxymethyl)-4-piperidinyl]-N-phenylpropanamide;R-30451;N-[4-(methoxymethyl)piperidin-4-yl]-N-phenylpropanamide
• CAS NO: 61086-18-8
• Molecular Formula: C₁₆H₂₄N₂O₂
• Molecular Weight: 276.37396
• EINECS: 262-598-1
• Mol File: 61086-18-8.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 389.5°C at 760 mmHg
• Flash Point: 189.4°C
• Appearance: /
• Density: 1.069g/cm³
• Vapor Pressure: 2.83E-06mmHg at 25°C
• Refractive Index: 1.536
• PKA: 9.77±0.10(Predicted)
• CAS DataBase Reference: N-[4-(methoxymethyl)piperidin-4-yl]-N-phenylpropionamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[4-(methoxymethyl)piperidin-4-yl]-N-phenylpropionamide(61086-18-8)
• EPA Substance Registry System: N-[4-(methoxymethyl)piperidin-4-yl]-N-phenylpropionamide(61086-18-8)

Safety Data

• Hazardous Substances Data: 61086-18-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C16H24N2O2/c1-3-15(19)18(14-7-5-4-6-8-14)16(13-20-2)9-11-17-12-10-16/h4-8,17H,3,9-13H2,1-2H3

Upstream product

• 61086-12-2 1-benzyl-4-[N-(1-oxopropyl)-N-phenylamino]-4-(methoxymethyl)piperidine 

Downstream Products

• 131728-91-1 N-[1-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-4-methoxymethyl-piperidin-4-yl]-N-phenyl-propionamide 
• 131727-83-8 N-{4-Methoxymethyl-1-[2-(5-methyl-furan-2-yl)-2-oxo-ethyl]-piperidin-4-yl}-N-phenyl-propionamide 
• 786601-28-3 N-<1-(2-hydroxypropyl)-4-(methoxymethyl)-4-piperidinyl>-N-phenylpropanamide 
• 69049-06-5 alfentanil hydrochloride 
• 84196-16-7 N-(4-(Methoxymethyl)piperidin-4-yl)-N-phenylpropionamide hydrochloride 
• 71195-58-9 alfentanil 

Relevant articles and documents

SUBSTITUTED 4-AMINO-PIPERIDINES

The present invention relates to new substituted 4-amino-piperidine opioid receptor modulators, pharmaceutical compositions thereof, and methods of use thereof

IMPROVED METHOD OF MAKING SUFENTANIL

The present invention relates to a process for the preparation of piperidine derivatives including sufentanil and its pharmaceutically acceptable salts, such as it citrate salt

N-(4-piperidinyl)-N-phenylamides and -carbamates

Novel N-(4-piperidinyl)-N-phenylamides and -carbamates having very potent analgesic activity, methods of preparing same and useful intermediates therefor.