611187-05-4 Usage
Description
2-(Benzyloxy)isoquinoline-1,3(2H,4H)-dione is an organic compound that serves as a key intermediate in the synthesis of various pharmaceutical compounds. It is characterized by the presence of a benzyloxy group attached to the isoquinoline core, which contributes to its unique chemical properties and reactivity.
Uses
Used in Pharmaceutical Industry:
2-(Benzyloxy)isoquinoline-1,3(2H,4H)-dione is used as an intermediate in the synthesis of 2-Hydroxyisoquinoline-1,3(2H,4H)-dione (H939800), a compound with potential antiviral properties. It plays a crucial role in the development of new drugs targeting HIV-1 integrase and the RNase H function of HIV-1 reverse transcriptase, offering a promising avenue for the treatment of HIV infections.
Used in Antiviral Research:
2-(Benzyloxy)isoquinoline-1,3(2H,4H)-dione is utilized in the study of antiviral agents, particularly focusing on its interaction with metal ions such as Mg2+ and Mn2+. Its ability to form complexes with these ions has been investigated using various spectroscopic techniques, providing valuable insights into its potential use as an antiviral agent.
Check Digit Verification of cas no
The CAS Registry Mumber 611187-05-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,1,1,1,8 and 7 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 611187-05:
(8*6)+(7*1)+(6*1)+(5*1)+(4*8)+(3*7)+(2*0)+(1*5)=124
124 % 10 = 4
So 611187-05-4 is a valid CAS Registry Number.
611187-05-4Relevant articles and documents
4-benzylideneisoquinoline-1,3(2H,4H)-diones as tyrosyl DNA phosphodiesterase 2 (TDP2) inhibitors
Senaweera, Sameera,He, Tianyu,Cui, Haixi,Aihara, Hideki,Wang, Zhengqiang
, p. 371 - 386 (2020/11/23)
Tyrosyl-DNA phosphodiesterase 2 (TDP2) repairs topoisomerase II (Top2) mediated DNA damages, including double-strand breaks (DSBs) that underpin the anticancer mechanism of clinical Top2 poisons such as etoposide (ETP). Inhibition of TDP2 could sensitize
Method for selection of hDIS3 PIN domain inhibitors and use of hDIS3 PIN domain inhibitors for cancer treatment
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Paragraph 0161-0162, (2016/04/22)
The present invention relates to a method for selection or screening of hDIS3 PIN domain inhibitors, yeast strain and cell line used in such methods It also relates to new therapeutic agents selected hDIS3 PIN domain inhibitors and uses thereof in the tre
