61137-53-9 Usage
Description
(4-[(2-fluoroethyl)(nitroso)carbamoyl]aminocyclohexyl)methyl acetate is a synthetic chemical compound derived from cyclohexane, featuring a cyclohexylmethyl acetate molecule with a fluoroethyl nitroso carbamoyl amino group. (4-[(2-fluoroethyl)(nitroso)carbamoyl]aminocyclohexyl)methyl acetate contains an acetate functional group and is characterized by the presence of nitroso and carbamoyl groups, which may exhibit biological or chemical reactivity. Due to its structural complexity and potential reactivity, it should be handled with caution, and its properties and applications should be thoroughly investigated before use.
Uses
Used in Pharmaceutical Applications:
(4-[(2-fluoroethyl)(nitroso)carbamoyl]aminocyclohexyl)methyl acetate is used as a potential pharmaceutical compound for its possible biological reactivity and chemical properties. The presence of the nitroso and carbamoyl groups may allow for interactions with biological targets, making it a candidate for drug development.
Used in Material Science Applications:
In the field of material science, (4-[(2-fluoroethyl)(nitroso)carbamoyl]aminocyclohexyl)methyl acetate may be utilized as a component in the development of new materials with specific properties. (4-[(2-fluoroethyl)(nitroso)carbamoyl]aminocyclohexyl)methyl acetate's structural features could contribute to the creation of materials with tailored characteristics for various applications.
Used in Chemical Research:
(4-[(2-fluoroethyl)(nitroso)carbamoyl]aminocyclohexyl)methyl acetate can be employed as a subject of chemical research to explore its reactivity, stability, and potential applications in various chemical processes. Understanding its properties can lead to the discovery of new reactions or the development of novel compounds with specific functions.
Used in the Synthesis of Other Compounds:
As a chemical intermediate, (4-[(2-fluoroethyl)(nitroso)carbamoyl]aminocyclohexyl)methyl acetate may be used in the synthesis of other complex molecules, particularly those with pharmaceutical or material science applications. Its unique structure could serve as a building block for the creation of new compounds with diverse properties and potential uses.
Check Digit Verification of cas no
The CAS Registry Mumber 61137-53-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,1,1,3 and 7 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 61137-53:
(7*6)+(6*1)+(5*1)+(4*3)+(3*7)+(2*5)+(1*3)=99
99 % 10 = 9
So 61137-53-9 is a valid CAS Registry Number.
61137-53-9Relevant articles and documents
Synthesis of analogues of N (2 chloroethyl) N' trans 4 methylcyclohexyl) N nitrosourea for evaluation as anticancer agents
Johnston,McCaleb,Clayton,Frye,Krauth,Montgomery
, p. 279 - 290 (2007/10/04)
The superior activity of N (2 chloroethyl) N' (trans 4 methylcyclohexyl) N nitrosourea (MeCCNU) against advanced murine Lewis lung carcinoma in comparisons with the cis form and other nitrosoureas prompted the synthesis of a number of MeCCNU analogues, including several cis trans pairs. The methyl group was replaced by a variety of substituents (CO2H, CH2CO2H, CO2Me, CH2OAc, CH2Cl, OMe); the trans 3 methylcyclohexyl, cis 2 methyl 1,3 dithian 5 yl, cis and trans 2 methyl 1,3 dithian 5 yl tetraoxide, and 1 methylhexyl (open chain) analogues were also prepared. Preliminary tests against murine leukemia L1210 revealed therapeutic indices (ED50/LD10) ranging from 0.26 to 0.79; all but 3 analogues effected 50% cure rates at nontoxic doses, the open chain analogue being one of the least active. In terms of therapeutic index, diequatorial (trans 4) isomers were, with one exception, as active as or, in 4 of the 8 examples, somewhat more active than the corresponding axial equatorial (cis 4) isomers. In this series, 4 of the 5 2-fluoroethyl analogues prepared were clearly inferior to the corresponding 2 chloroethyl analogues.
