6120-96-3 Usage
Description
Cyclopropanecarboxamide, 1-phenyl(7CI,8CI,9CI), also known as 1-phenylcyclopropanecarboxamide, is a chemical compound belonging to the cyclopropane carboxamide family. It has the molecular formula C9H9NO and is recognized for its unique properties and reactivity, making it a significant compound in the realm of organic chemistry.
Uses
Used in Organic Synthesis:
Cyclopropanecarboxamide, 1-phenyl(7CI,8CI,9CI) is utilized as a building block in organic synthesis for the creation of new compounds and molecules. Its cyclopropyl group can be incorporated into various organic molecules, enhancing their properties and applications.
Used in Pharmaceutical Research:
In the pharmaceutical industry, Cyclopropanecarboxamide, 1-phenyl(7CI,8CI,9CI) serves as a key component in the development of new drugs. Its unique structure and reactivity contribute to the design and synthesis of innovative pharmaceutical agents with potential therapeutic benefits.
Used in Agrochemical Development:
Cyclopropanecarboxamide, 1-phenyl(7CI,8CI,9CI) is also employed in the agrochemical sector for the development of new agrochemicals. Its cyclopropyl group can be integrated into molecules to improve their effectiveness in agricultural applications, such as pest control and crop protection.
Used as a Reagent in Chemical Reactions:
In addition to its applications in synthesis and research, Cyclopropanecarboxamide, 1-phenyl(7CI,8CI,9CI) is used as a reagent in chemical reactions to introduce the cyclopropyl group into organic molecules. This ability to modify the structure of other compounds makes it a versatile tool in the field of organic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 6120-96-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,1,2 and 0 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 6120-96:
(6*6)+(5*1)+(4*2)+(3*0)+(2*9)+(1*6)=73
73 % 10 = 3
So 6120-96-3 is a valid CAS Registry Number.
InChI:InChI=1/C10H11NO/c11-9(12)10(6-7-10)8-4-2-1-3-5-8/h1-5H,6-7H2,(H2,11,12)
6120-96-3Relevant articles and documents
Cloke,Knowles,Anderson
, p. 2547 (1936)
Bromomethyl Silicate: A Robust Methylene Transfer Reagent for Radical-Polar Crossover Cyclopropanation of Alkenes
Luo, Wenping,Fang, Yewen,Zhang, Li,Xu, Tianhang,Liu, Yongjun,Li, Yan,Jin, Xiaoping,Bao, Jiakan,Wu, Xiaodong,Zhang, Zongyong
supporting information, p. 1778 - 1781 (2020/03/11)
A general protocol for visible-light-induced cyclopropanation of alkenes was developed with bromomethyl silicate as a methylene transfer reagent, offering a robust tool for accessing highly valuable cyclopropanes. In addition to α-aryl or methyl-substituted Michael acceptors and styrene derivatives, the unactivated 1,1-dialkyl ethylenes were also shown to be viable substrates. Apart from realizing the cyclopropanation of terminal alkenes, the methyl transfer reaction has been further demonstrated to be amenable to the internal olefins. The photocatalytic cyclopropanation of 1,3-bis(1-arylethenyl)benzenes was also achieved, giving polycyclopropane derivatives in excellent yields. With late-stage cyclopropanation as the key strategy, the synthetic utility of this transformation was also demonstrated by the total synthesis of LG100268.
Visible-Light-Promoted Redox-Neutral Cyclopropanation Reactions of α-Substituted Vinylphosphonates and Other Michael Acceptors with Chloromethyl Silicate as Methylene Transfer Reagent
Guo, Ting,Zhang, Li,Liu, Xiaobo,Fang, Yewen,Jin, Xiaoping,Yang, Yi,Li, Yan,Chen, Bin,Ouyang, Minghui
supporting information, p. 4459 - 4463 (2018/09/14)
The alkene cyclopropanation with chloromethyl silicate as a methylene transfer reagent has been accomplished via visible-light-mediated redox-neutral catalysis. This method features broad functional group tolerance and mild conditions. In addition to α-substituted vinylphosphonates, a range of Michael acceptors including α,β-unsaturated acrylate, ketone, amide and sulfone are suitable substrates for this photocatalytic cyclopropanation. An application of this protocol to the cyclopropanation of estrone derivative is also presented. (Figure presented.).
