61207-11-2

Basic information

• Product Name: 3-Isoxazolecarbonitrile, 4,5-dihydro-5-(4-methylphenyl)-, 2-oxide
• CAS NO: 61207-11-2
• Molecular Formula: C11H10N2O2
• Molecular Weight: 202.213
• Mol File: 61207-11-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-Isoxazolecarbonitrile, 4,5-dihydro-5-(4-methylphenyl)-, 2-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Isoxazolecarbonitrile, 4,5-dihydro-5-(4-methylphenyl)-, 2-oxide(61207-11-2)
• EPA Substance Registry System: 3-Isoxazolecarbonitrile, 4,5-dihydro-5-(4-methylphenyl)-, 2-oxide(61207-11-2)

Safety Data

• Hazardous Substances Data: 61207-11-2(Hazardous Substances Data)

Upstream product

• 61207-09-8 3-nitro-2-(2-nitro-1-p-tolyl-ethoxy)-5-p-tolyl-isoxazolidine-3-carbonitrile 
• 1355229-73-0 5-(4-methylphenyl)-2-[1-(4-methylphenyl)-2-nitroethoxy]-1,2-oxazolidine-3,3-dicarbonitrile 
• 79574-32-6 2-(p-tolyl)cyclopropane-1,1-dicarbonitrile 

Relevant articles and documents

3-cyanoisoxazoline N-oxide compound and synthesis method thereof

The invention discloses a 3-cyanoisoxazoline N-oxide compound and a synthesis method thereof. The structural formula of the prepared compound is shown in the specification. In the formula, R is a phenyl, 4-methylphenyl, 4-tert-butylphenyl, 4-isopropyl phenyl, 4-methoxyphenyl, 4-trifluoromethylphenyl, 4-fluorophenyl, 4-chlorphenyl, 4-bromophenyl, 4-(1,1'-biphenyl), 2-acetoxyphenyl, 2-naphthyl, 2-thienyl, or 5-(benzo-1,3-dioxocyclopentane)yl group. According to the invention, copper nitrate trihydrate is used as a nitrogen and oxygen source, dimethyl sulfoxide is used as a solvent, the raw materials are simple and easy to obtain, operation is simple, conditions are mild, reaction is environment-friendly, and yield is generally excellent. The 3-cyanoisoxazoline N-oxide compound synthesized by applying the method disclosed by the invention has potential application value in organic synthesis and medicinal chemistry, and has a relatively good application prospect in industrial production.