612530-44-6 Usage
Description
5-Phenyl-1,2,5-thiadiazolidin-3-one 1,1-dioxide is a chemical compound characterized by its unique molecular structure, which features a thiazolidinone ring fused with a phenyl group and an additional dioxide group. 5-Phenyl-1,2,5-thiadiazolidin-3-one 1,1-dioxide is known for its potential applications in various fields due to its distinct chemical properties.
Uses
Used in Pharmaceutical Industry:
5-Phenyl-1,2,5-thiadiazolidin-3-one 1,1-dioxide is used as a key component in the structure-based design of protein tyrosine phosphatase-1B (PTP-1B) inhibitors. PTP-1B is an enzyme that plays a crucial role in various cellular processes, including signal transduction and regulation of glucose homeostasis. Inhibiting this enzyme has been shown to have potential therapeutic benefits in treating type 2 diabetes, obesity, and other related metabolic disorders.
In the pharmaceutical industry, 5-Phenyl-1,2,5-thiadiazolidin-3-one 1,1-dioxide serves as a valuable building block for the development of novel PTP-1B inhibitors. These inhibitors can modulate the activity of the enzyme, thereby providing a potential treatment option for patients suffering from metabolic diseases.
Additionally, the compound's unique structure may also make it a candidate for further research and development in other therapeutic areas, such as oncology or neurodegenerative diseases, where protein tyrosine phosphatases are known to play a role in disease progression.
Check Digit Verification of cas no
The CAS Registry Mumber 612530-44-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,1,2,5,3 and 0 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 612530-44:
(8*6)+(7*1)+(6*2)+(5*5)+(4*3)+(3*0)+(2*4)+(1*4)=116
116 % 10 = 6
So 612530-44-6 is a valid CAS Registry Number.
612530-44-6Relevant articles and documents
Structure-based design of protein tyrosine phosphatase-1B inhibitors
Black, Emma,Breed, Jason,Breeze, Alexander L.,Embrey, Kevin,Garcia, Robert,Gero, Thomas W.,Godfrey, Linda,Kenny, Peter W.,Morley, Andrew D.,Minshull, Claire A.,Pannifer, Andrew D.,Read, Jon,Rees, Amanda,Russell, Daniel J.,Toader, Dorin,Tucker, Julie
, p. 2503 - 2507 (2005)
Using structure-based design, a new class of inhibitors of protein tyrosine phosphatase-1B (PTP1B) has been identified, which incorporate the 1,2,5-thiadiazolidin-3-one-1,1-dioxide template.
