6127-18-0

Basic information

• Product Name: 2-CYANO-N-(4-METHYLPHENYL)ETHANETHIOAMIDE
• Synonyms: 2-CYANO-N-(4-METHYLPHENYL)ETHANETHIOAMIDE;TOSLAB 23085;1H-Indole,4-bromo-2-methyl-;4-BroMo-2-Methyl-1H-indole;4-BroMo-2-Methylindole
• CAS NO: 6127-18-0
• Molecular Formula: C₉H₈BrN
• Molecular Weight: 190.26
• Mol File: 6127-18-0.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-CYANO-N-(4-METHYLPHENYL)ETHANETHIOAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CYANO-N-(4-METHYLPHENYL)ETHANETHIOAMIDE(6127-18-0)
• EPA Substance Registry System: 2-CYANO-N-(4-METHYLPHENYL)ETHANETHIOAMIDE(6127-18-0)

Safety Data

• Hazardous Substances Data: 6127-18-0(Hazardous Substances Data)

Usage

General Description

2-Cyano-N-(4-methylphenyl)ethanethioamide is a synthetic organic compound that belongs to the group of thioamides and nitriles. It is characterized by the presence of sulfide, methyl group, amine, and nitrile functional groups in its structure. The formula of this compound is C11H12N2S. The presence of these functional groups suggests that this compound could display a range of chemical behavior, including possible reactivity with both acids and bases. It's typically used in the field of pharmaceuticals or organic synthetic research, thus indicating potential bioactive properties. Being a chemical compound, handling and disposal should always adhere to appropriate safety precautions.

Upstream product

• 877203-66-2 2-(2-bromophenyl)-3-methyl-2H-azirine 
• 52488-36-5 4-bromo-1H-indole 
• 412048-77-2 1‐(benzenesulfonyl)‐4‐bromo‐1H‐indole 
• 1232861-11-8 4-bromo-2-methyl-1-(phenylsulfonyl)-1H-indole 
• 21906-31-0 1-(2-bromophenyl)propane-2-one 

Downstream Products

• 34058-51-0 methyl 2-methyl-1H-indole-4-carboxylate 
• 1542706-34-2 1-(4-(benzylamino)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-2-yl)-2-methyl-1H-indole-4-carboxylic acid 
• 1542706-15-9 1-(4-(benzylamino)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-2-yl)-N,2-dimethyl-1H-indole-4-carboxamide 
• 1542711-68-1 methyl 1-(4-(benzylamino)-5,6,7,8-tetrahydroquinazolin-2-yl)-2-methyl-1H-indole-4-carboxylate 
• 1542706-36-4 1-(4-(benzylamino)-5,6,7,8-tetrahydroquinazolin-2-yl)-2-methyl-1H-indole-4-carboxylic acid 
• 1360883-22-2 2-methyl-1H-indole-4-carbonitrile 
• 1542705-09-8 1-(4-(benzylamino)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-2-yl)-2-methyl-1H-indole-4-carbonitrile 
• 1542705-83-8 1-(4-(benzylamino)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-2-yl)-2-methyl-1H-indole-4-carbonitrile 
• 1542705-59-8 1-[4-(benzylamino)-5,6,7,8-tetrahydroquinazolin-2-yl]-2-methyl-1H-indole-4-carbonitrile 
• 1542706-02-4 1-(4-(benzylamino)-5,6,7,8-tetrahydroquinazolin-2-yl)-2-methyl-1H-indole-4-carboxamide 
• 1542705-58-7 1-(4-(benzylamino)-5,6,7,8-tetrahydropyrido[4,3-d]-pyrimidin-2-yl)-2-methyl-1H-indole-4-carboxamide 
• 955979-22-3 2-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole 
• 34058-50-9 2-methyl-1H-indole-4-carboxylic acid 

Relevant articles and documents

Modulators of the Cystic Fibrosis Transmembrane Conductance Regulator Protein and Methods of Use

The invention discloses compounds of Formula (I), wherein A1, R1, R2, R3, R4, and n are as defined herein. The present invention relates to compounds and their use in the treatment of cystic fibrosis, methods for their production, pharmaceutical compositions comprising the same, and methods of treating cystic fibrosis by administering a compound of the invention.

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Fused pyrimidine compounds having a saturated, unsaturated or aromatic A ring fused to a pyrimidine ring and having a complex substituents at the 2 position and a substituted amine at the 4 position of the pyrimidine ring as well as optional aliphatic, functional and/or aromatic components substituted at other positions of the pyrimidine ring and A ring are disclosed. These compounds are inhibitors of the AAA proteasome complex containing p97 and are effective medicinal agents for treatment of diseases associated with p97 bioactivity such as cancer.

ETHYNYLINDOLE COMPOUNDS

As a compound having a potent oral activity and a long-lasting cysLT1/cysLT2 receptor antagonistic activity, the compound of the formula (I): which exhibits potent antagonistic activity against the cysLT1/cysLT2 /sub