61312-84-3 Usage
Description
(4-Nitrophenyl)methyl 3-oxobutanoate, also known as 4-Nitrobenzyl Acetoacetate, is an organic compound that serves as a reagent in the synthesis of various pharmaceuticals and chemicals. It is characterized by its ester linkage and the presence of a nitro group on the phenyl ring, which can be reduced to an amine group under certain conditions.
Uses
Used in Pharmaceutical Industry:
(4-Nitrophenyl)methyl 3-oxobutanoate is used as a reagent in the preparation of panipenem, a new carbapenem antibiotic for the treatment of inflammation. It is involved in the esterification of nitrobenzyl alcohol, followed by substitution, cyclizations, and hydrogenation to produce the final antibiotic compound.
Used in Chemical Synthesis:
(4-Nitrophenyl)methyl 3-oxobutanoate can be utilized in the synthesis of other organic compounds, such as dyes, pigments, and pharmaceutical intermediates. Its reactivity and functional groups make it a versatile building block in organic chemistry.
Used in Research and Development:
(4-Nitrophenyl)methyl 3-oxobutanoate can also be employed in research and development settings to study the reactivity of nitro groups and ester linkages, as well as to explore new synthetic routes and methodologies in organic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 61312-84-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,1,3,1 and 2 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 61312-84:
(7*6)+(6*1)+(5*3)+(4*1)+(3*2)+(2*8)+(1*4)=93
93 % 10 = 3
So 61312-84-3 is a valid CAS Registry Number.
InChI:InChI=1/C11H11NO5/c1-8(13)6-11(14)17-7-9-2-4-10(5-3-9)12(15)16/h2-5H,6-7H2,1H3
61312-84-3Relevant articles and documents
Atypical Carbapenem Antibiotics with Improved Activity Against Carbapenemase-Producing Acinetobacter baumannii
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Paragraph 0021, (2020/11/30)
The following invention deals with the design, preparation, evaluation, and use of carbapenem antibiotics with improved activity, relative to current commercially available carbapenem antibiotics, against infections involving multidrug resistant, carbapen
Metal salts as novel catalysts for efficient transesterification of β-ketoesters
Bandgar,Sadavarte,Uppalla
, p. 2063 - 2066 (2007/10/03)
Ethyl/methyl β-ketoesters with alcohols in presence of catalytic amount of anhydrous metal salts (FeSO4, CuSO4) undergo smooth transesterification.
Solvent-free microwave-assisted organic reactions prepation of β-keto esters
Gianotti, Massimo,Martelli, Giorgio,Spunta, Giuseppe,Campana, Eileen,Panunrio, Mauro,Mendozza, Monica
, p. 1725 - 1730 (2007/10/03)
Microwave technique has been utilised in the preparation of β-keto esters. Two different procedures are described: transesterification of β- keto esters and ring opening of 2,2,6-trimethyl-1,3-dioxin-4-one.
