61326-02-1

Basic information

• Product Name: 10-piperazin-1-yl-4H-thieno[3,2-b][1,5]benzodiazepine
• Synonyms: 10-(piperazin-1-yl)-4H-thieno[3,2-b][1,5]benzodiazepine; 4H-thieno[3,2-b][1,5]benzodiazepine, 10-(1-piperazinyl)-
• CAS NO: 61326-02-1
• Molecular Formula: C₁₅H₁₆N₄S
• Molecular Weight: 284.3793
• Mol File: 61326-02-1.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 479.9°C at 760 mmHg
• Flash Point: 244°C
• Density: 1.42g/cm³
• Vapor Pressure: 2.27E-09mmHg at 25°C
• Refractive Index: 1.763
• CAS DataBase Reference: 10-piperazin-1-yl-4H-thieno[3,2-b][1,5]benzodiazepine(CAS DataBase Reference)
• NIST Chemistry Reference: 10-piperazin-1-yl-4H-thieno[3,2-b][1,5]benzodiazepine(61326-02-1)
• EPA Substance Registry System: 10-piperazin-1-yl-4H-thieno[3,2-b][1,5]benzodiazepine(61326-02-1)

Safety Data

• Hazardous Substances Data: 61326-02-1(Hazardous Substances Data)

Usage

Chemical class

Belongs to the benzodiazepine class of drugs.

Mechanism of action

Acts as a subtype-selective modulator of the GABAA receptor.

Target receptors

Specifically targets the α2/α3-containing GABAA receptors.

Potential therapeutic applications

Studied for its potential use in treating anxiety, insomnia, and other neurological disorders.

Preclinical studies

Demonstrated anxiolytic and sedative effects with minimal cognitive impairment and motor coordination disruption.

Current status

Still under investigation for its therapeutic potential and safety profile.
Please note that this list is based on the limited information provided in the material. Additional research and data may reveal more properties and specific content about TPA-023.

Relevant articles and documents

Thieno[3,2-b]-[1,5]benzodiazepines

Thieno[1,5]benzodiazepines having useful CNS activity containing the novel tricyclic ring system: STR1 the 10-position being substituted by an amino, preferably a piperazino, group.