61394-49-8 Usage
Description
Ethyl 2-oxoindoline-5-carboxylate is a chemical compound with the molecular formula C11H11NO3. It is a derivative of indole, a heterocyclic compound commonly found in plants and natural products. Its structure and reactivity make it a versatile starting material for the synthesis of various biologically active compounds.
Uses
Used in Pharmaceutical Research:
Ethyl 2-oxoindoline-5-carboxylate is used as a building block in organic synthesis and pharmaceutical research, particularly in the development of drugs targeting dopamine receptors in the central nervous system.
Used in Anti-inflammatory Applications:
Ethyl 2-oxoindoline-5-carboxylate has been investigated for its potential anti-inflammatory properties, making it a candidate for the development of anti-inflammatory drugs.
Used in Anticancer Applications:
Ethyl 2-oxoindoline-5-carboxylate has also been investigated for its potential anticancer properties, indicating its potential use in the development of cancer treatments.
Used in Organic Synthesis:
Ethyl 2-oxoindoline-5-carboxylate is used as a versatile starting material in organic synthesis, enabling the creation of a wide range of biologically active compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 61394-49-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,1,3,9 and 4 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 61394-49:
(7*6)+(6*1)+(5*3)+(4*9)+(3*4)+(2*4)+(1*9)=128
128 % 10 = 8
So 61394-49-8 is a valid CAS Registry Number.
61394-49-8Relevant articles and documents
An efficient synthesis of a spirocyclic oxindole analogue
Teng, Dawei,Zhang, Hongxing,Mendonca
, p. 700 - 706 (2006)
An efficient, scaleable synthesis approach towards the spirocyclic oxindole analogue 1′-(tert-butoxycarbonyl)-2-oxospiro[indoline-3,4′- piperidine]-5-carboxylic acid (1) is described. The key steps are dianion alkylation and cyclization of ethyl 2-oxindoline-5-carboxylate (4) and demethylation of the resulting spirocyclic oxindole ethyl 1′-methyl-2- oxospiro[indoline-3,4′-piperidine]-5-carboxylate (5). The target compound was obtained in an overall yield of 35 % over eight steps without resorting to chromatographic purification.
Studies on positive inotropic agents. V. Synthesis of 1-heteroaroylpiperazine derivatives
Ogawa,Tamada,Fujioka,Teramoto,Kondo,Yamashita,Yabuuchi,Tominaga,Nakagawa
, p. 2253 - 2258 (2007/10/02)
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