6142-90-1 Usage
Description
Furan-D4, a five-membered heterocyclic aromatic ring, is a deuterated analogue of Furan. It is a colorless to light yellow liquid with unique chemical properties that make it a valuable compound in various applications.
Uses
Used in Chemical Synthesis:
Furan-D4 is used as a building block for the preparation of many heterocyclic compounds. Its deuterated nature provides specific advantages in chemical reactions, such as improved stability and reduced reactivity, which can be beneficial for the synthesis of complex molecules.
Used in Pharmaceutical Industry:
Furan-D4 is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique properties allow for the development of new drugs with improved efficacy and reduced side effects.
Used in Material Science:
Furan-D4 is employed in the development of novel materials with specific properties, such as enhanced stability or altered reactivity. Its incorporation into polymers and other materials can lead to improved performance in various applications.
Used in Research and Development:
As a labelled analogue of Furan, Furan-D4 is used in research and development for studying the effects of deuteration on chemical reactions and understanding the fundamental properties of heterocyclic compounds. This knowledge can be applied to the design of new drugs, materials, and other chemical products.
Check Digit Verification of cas no
The CAS Registry Mumber 6142-90-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,1,4 and 2 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 6142-90:
(6*6)+(5*1)+(4*4)+(3*2)+(2*9)+(1*0)=81
81 % 10 = 1
So 6142-90-1 is a valid CAS Registry Number.
InChI:InChI=1/C4H4O/c1-2-4-5-3-1/h1-4H/i1D,2D,3D,4D
6142-90-1Relevant articles and documents
Heterolytic Oxidative Addition of sp2and sp3C-H Bonds by Metal-Ligand Cooperation with an Electron-Deficient Cyclopentadienone Iridium Complex
Higashi, Takuya,Kusumoto, Shuhei,Nozaki, Kyoko
supporting information, p. 12999 - 13004 (2021/08/16)
Oxidative addition reactions of C-H bonds that generate metal-carbon-bond-containing reactive intermediates have played essential roles in the field of organometallic chemistry. Herein, we prepared a cyclopentadienone iridium(I) complex 1 designed for oxidative C-H bond additions. The complex cleaves the various sp2 and sp3 C-H bonds including those in hexane and methane as inferred from their H/D exchange reactions. The hydroxycyclopentadienyl(nitromethyl)iridium(III) complex 2 was formed when the complex was treated with nitromethane, which highlights this elementary metal-ligand cooperative C-H bond oxidative addition reaction. Mechanistic investigations suggested the C-H bond cleavage is mediated by polar functional groups in substrates or another iridium complex. We found that ligands that are more electron-deficient lead to more favorable reactions, in sharp contrast to classical metal-centered oxidative additions. This trend is in good agreement with the proposed mechanism, in which C-H bond cleavage is accompanied by two-electron transfer from the metal center to the cyclopentadienone ligand. The complex was further applied to catalytic transfer-dehydrogenation of tetrahydrofuran (THF).
