61422-43-3Relevant articles and documents
Iron-Catalysed Reductive Amination of Carbonyl Derivatives with Ω-Amino Fatty Acids to Access Cyclic Amines
Wei, Duo,Netkaew, Chakkrit,Carré, Victor,Darcel, Christophe
, p. 3008 - 3012 (2019/05/15)
An efficient method for the reductive amination of carbonyl derivatives with ω-amino fatty acids catalysed by an iron complex Fe(CO)4(IMes) [IMes=1,3-bis(2,4,6-trimethylphenyl)imidazol-2-ylidene] by means of hydrosilylation was developed. A variety of pyrrolidines, piperidines and azepanes were selectively synthesised in moderate-to-excellent yields (36 examples, 47–97 % isolated yield) with a good functional group tolerance.
N-alkylation of amines under microwave irradiation: Modified eschweiler-clarke reaction
Torchy,Barbry
, p. 292 - 293 (2007/10/03)
The N-alkylation of hexahydroazepine and benzylamine is performed under microwave irradiation in the presence of formic acid and different aldehydes or ketones. Good yields were obtained with reactive carbonyl compounds.