61424-76-8

Basic information

• Product Name: 2-AMINO-3-FORMYLCHROMONE
• Synonyms: 2-amino-4-oxo-chromene-3-carbaldehyde;2-amino-4-oxochromene-3-carbaldehyde;2-AMINO-3-FORMYLCHROMONE;2-AMINO-4-OXO-4 H-1-BENZOPYRAN-3-CARBOXALDEHYDE;2-AMINO-4-OXO-4H-CHROMENE-3-CARBALDEHYDE;2-Aminochromone-3-carboxaldehyde;2-amino-4-keto-chromene-3-carbaldehyde;2-amino-4-oxo-3-chromenecarboxaldehyde
• CAS NO: 61424-76-8
• Molecular Formula: C₁₀H₇NO₃
• Molecular Weight: 189.17
• Product Categories: Chromones;Heterocyclic Compounds
• Mol File: 61424-76-8.mol
• Article Data: 1

Chemical Properties

• Melting Point: 249 °C (dec.)(lit.)
• Boiling Point: 401.2°C at 760 mmHg
• Flash Point: 241°C
• Appearance: /
• Density: 1.486g/cm³
• Vapor Pressure: 1.2E-06mmHg at 25°C
• Refractive Index: 1.713
• PKA: 1.31±0.20(Predicted)
• CAS DataBase Reference: 2-AMINO-3-FORMYLCHROMONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-3-FORMYLCHROMONE(61424-76-8)
• EPA Substance Registry System: 2-AMINO-3-FORMYLCHROMONE(61424-76-8)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 61424-76-8(Hazardous Substances Data)

Usage

Description

2-AMINO-3-FORMYLCHROMONE is a chemical compound that serves as a key intermediate in the synthesis of various organic compounds and pharmaceuticals. It is characterized by its unique structure, which includes an amino group at the 2nd position and a formyl group at the 3rd position of the chromone ring system. 2-AMINO-3-FORMYLCHROMONE plays a crucial role in the preparation of chiral Schiff base ligands and other heterocyclic Schiff's bases with potential applications in various fields.

Uses

Used in Pharmaceutical Industry:
2-AMINO-3-FORMYLCHROMONE is used as a key intermediate for the synthesis of chiral Schiff base ligands, which are essential in the development of new pharmaceuticals and drug candidates. These ligands can be used in asymmetric catalysis, a technique that allows for the selective synthesis of enantiomerically pure compounds, which are important in the pharmaceutical industry due to their potential therapeutic effects.
Used in Antimicrobial Applications:
2-AMINO-3-FORMYLCHROMONE is used as a precursor in the synthesis of heterocyclic Schiff's bases with antimicrobial activity. These compounds can be used as potential antimicrobial agents, helping to combat bacterial and fungal infections.
Used in Organic Synthesis:
2-AMINO-3-FORMYLCHROMONE is used as a starting material for the preparation of various organic compounds, including hydrazone derivatives, benzofuran-2-carboxamides, and pyrrole-2-carboxamides. These compounds have potential applications in various fields, such as pharmaceuticals, agrochemicals, and materials science.
Used in Research and Development:
2-AMINO-3-FORMYLCHROMONE is used as a research compound in the development of new synthetic methods and strategies for the preparation of complex organic molecules. Its unique structure and reactivity make it an interesting target for chemists working in the field of organic synthesis.

InChI:InChI=1/C10H7NO3/c11-10-7(5-12)9(13)6-3-1-2-4-8(6)14-10/h1-5H,11H2

Upstream product

• 50743-17-4 4-oxo-4H-1-benzopyran-3-carbonitrile 
• 107-15-3 ethylenediamine 

Downstream Products

• 1301190-16-8 2-amino-3-(2-hydroxyphenyliminomethyl)chromone 
• 91546-70-2 2-amino-3-[(2-phenylhydrazinylidene)methyl]chromone 
• 1584653-09-7 (Z)-3-(2'-amino-4-oxo-4H-chromen-3-yl)-2-(4''-nitrophenyl)acrylonitrile 
• 1331865-64-5 4-{N'-[1-(2-amino-4-oxo-chromen-3-yl)meth-(E)-ylidene]hydrazino}benzoic acid 
• 1214886-97-1 N'-[(2-amino-4-oxo-4H-chromen-3-yl)methylene]benzohydrazide 
• 1214887-10-1 3-{[(2-acetylphenyl)imino]methyl}-2-amino-4H-chromen-4-one 
• 1214887-11-2 4-{[(2-amino-4-oxo-4H-chromen-3-yl)methylene]amino}-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one 
• 1028435-80-4 C₁₉H₁₃NO₂ 
• 1028435-82-6 C₁₉H₁₃NO₂ 
• 1028435-78-0 C₁₈H₁₁NO₂ 
• 869637-43-4 2-(4-chlorophenyl)-5-oxo-5H-chromeno[2,3-b]pyridine-3-carbonitrile 
• 1076-38-6 4-hydroxy[1]benzopyran-2-one 
• 73262-21-2 2-(4-oxo-4H-[1]benzopyran-3-yl) [1] benzopyrano[3,2-e]pyrimidin-5(5H)-one 
• 90701-02-3 Bis-<1>benzopyrano<2,3-b:3',2'-e>pyridin-5(5H),7(7H)-dion 

Relevant articles and documents

Heterocyclic Systems. 8. Condensation Reactions of 4-Oxo-4H-benzopyran-3-carbonitrile

Condensation reactions of 4-oxo-4H-benzopyran-3-carbonitriles (1; X=H, CH3, Cl, and Br) with 1,2-diamines, acetylglycine, and themselves have been investigated.The compounds 1 on being refluxed with ethylenediamine in ethanol give initially 1,4-additio