61466-03-3

Basic information

• Product Name: 3H-Pyrazol-3-one, 2,4-dihydro-4-[(5-hydroxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)methylene] -5-methyl-2-phenyl-, (4Z)-
• Synonyms: 4,4'-methylidenebis(3-methyl-1-phenyl-5-pyrazolone);5,5'-dimethyl-2,2'-diphenyl-1,2,2',4'-tetrahydro-4,4'methanylylidene-bis-pyrazol-3-one;4,4'-methylidenebis(1-phenyl-3-methylpyrazol-5-one);4,4-methylidenebis(1-phenyl-3-methylpyrazol-5-one);5-Oxo-3-methyl-1-phenyl-4-[5-oxo-3-methyl-1-phenyl-4,5-dihydro-pyrazolidenmethyl]-4,5-dihydro-pyrazol
• CAS NO: 61466-03-3
• Molecular Formula: C21H18N4O2
• Molecular Weight: 358.4
• Mol File: 61466-03-3.mol
• Article Data: 19

Chemical Properties

• CAS DataBase Reference: 3H-Pyrazol-3-one, 2,4-dihydro-4-[(5-hydroxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)methylene] -5-methyl-2-phenyl-, (4Z)-(CAS DataBase Reference)
• NIST Chemistry Reference: 3H-Pyrazol-3-one, 2,4-dihydro-4-[(5-hydroxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)methylene] -5-methyl-2-phenyl-, (4Z)-(61466-03-3)
• EPA Substance Registry System: 3H-Pyrazol-3-one, 2,4-dihydro-4-[(5-hydroxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)methylene] -5-methyl-2-phenyl-, (4Z)-(61466-03-3)

Safety Data

• Hazardous Substances Data: 61466-03-3(Hazardous Substances Data)

Upstream product

• 611-35-8 4-chloroquinoline 
• 89-25-8 edaravone 
• 136806-18-3 4-amino-2-oxo-2H-chromene-3-carbaldehyde 
• 59-88-1 phenylhydrazine hydrochloride 
• 141-97-9 ethyl acetoacetate 
• 68-12-2 N,N-dimethyl-formamide 
• 122-51-0 orthoformic acid triethyl ester 
• 127-08-2 potassium acetate 
• 118-92-3 anthranilic acid 
• 7357-70-2 Cyanothioacetamide 
• 41927-23-5 4-bromo-3-methyl-1-phenylpyrazol-5-one 
• 2032-35-1 Bromoacetaldehyde diethyl acetal 
• 74451-57-3 (E)-5,5'-dimethyl-2,2'-diphenyl-2H,2'H-[4,4']bipyrazolylidene-3,3'-dione 
• 68719-56-2 4-bromo-5-methyl-2-phenyl-1,2-dihydro-pyrazol-3-one 

Relevant articles and documents

Straightforward synthesis of diverse dipyrazolylmethane derivatives and their application for fluorescence sensing of Cu2+ ions

A variety of dipyrazolylmethane derivatives were synthesized from the reactions of readily available β-keto esters with arylhydrazine hydrochlorides and DMF in the presence of p-toluenesulfonic acid (p-TsOH). This methodology provides a concise and practical one-pot route for the construction of diverse dipyrazolylmethane derivatives in good yield. As an application, the synthesized nitro-substituted compound displayed an excellent turn-off fluorescence sensing property for the detection of Cu2+ ions.

Reaction of 2-chloro-1-alkyl-1H-indole-3-carbaldehydes with barbituric acids and 5-methyl-2-phenyl-2,4-dihydropyrazol-3-one. Formation of compound with extremely short intramolecular hydrogen bond in eight-membered pseudocycle

New indolin-2-one derivatives, containing in its molecules eight-membered pseudo-cycle with unusually short intramolecular hydrogen bond in OHO-bridge have been synthesized by reaction of 2-chloro-1-alkyl-1H-indole-3-carbaldehyde with barbituric acids or 5-methyl-2-phenyl-2,4-dihydropyrazol-3-one. Under the action of amines they undergo fragmentation to 5-aminomethylenebarbituric acids or 4-aminomethylenepyrazolones and 1-alkyl-1,3-dihydroindol-2-ones.

Friedlander synthesis of novel benzopyranopyridines in the presence of chitosan as heterogeneous, efficient and biodegradable catalyst under solvent-free conditions

Efficient synthesis of benzopyrano[4,3-b]pyridine derivatives was achieved from 4-amino-3-formylcoumarin and different active methylene compounds under solvent-free thermal heating at 80 °C via Friedlander condensation in the presence of chitosan as heterogeneous, basic green catalyst. The present methodology is a novel green approach to benzopyranopyridine. It offers several advantages such as shorter reaction time, mild reaction conditions, simple operational procedure, use of recyclable and biodegradable catalyst.