616224-06-7

Basic information

• Product Name: 2-[(1-tert-butoxycarbonyl-piperidin-4-ylmethyl)-amino]-1H-benzimidazole-4-carboxylic acid methyl ester
• CAS NO: 616224-06-7
• Molecular Weight: 388.467
• Mol File: 616224-06-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-[(1-tert-butoxycarbonyl-piperidin-4-ylmethyl)-amino]-1H-benzimidazole-4-carboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[(1-tert-butoxycarbonyl-piperidin-4-ylmethyl)-amino]-1H-benzimidazole-4-carboxylic acid methyl ester(616224-06-7)
• EPA Substance Registry System: 2-[(1-tert-butoxycarbonyl-piperidin-4-ylmethyl)-amino]-1H-benzimidazole-4-carboxylic acid methyl ester(616224-06-7)

Safety Data

• Hazardous Substances Data: 616224-06-7(Hazardous Substances Data)

Upstream product

• 107582-20-7 2,3-diaminobenzoic acid methyl ester 
• 144222-22-0 tert-butyl 4-(aminomethyl)piperidine-1-carboxylate 

Relevant articles and documents

PIPERIDINE DERIVATIVES HAVING CCR3 ANTAGONISM

The invention provides low molecular compounds having activity which inhibits binding of CCR3 ligands to CCR3 on target cells, i.e. CCR3 antagonists. The invention also provides compounds represented by formula (I) below, pharmaceutically acceptable acid adducts thereof, or pharmaceutically acceptable C1-C6 alkyl adducts thereof, as well as pharmaceutical compositions comprising them as effective ingredients, which are useful for treatment or prevention of diseases associated with CCR3, such as asthma and allergic rhinitis.