61687-26-1

Basic information

• Product Name: 7-Chloro-2-phenyl-quinoline
• Synonyms: 7-Chloro-2-phenyl-quinoline;2-Phenyl-7-chloroquinoline
• CAS NO: 61687-26-1
• Molecular Formula: C₁₅H₁₀ClN
• Molecular Weight: 239.6996
• EINECS: 1312995-182-4
• Mol File: 61687-26-1.mol
• Article Data: 29

Chemical Properties

• Melting Point: 105-106℃ (ethyl ether )
• Boiling Point: 394.0±27.0 °C(Predicted)
• Appearance: /
• Density: 1.235±0.06 g/cm3 (20℃ 760 Torr)
• Storage Temp.: 2-8°C
• PKA: 3.01±0.14(Predicted)
• CAS DataBase Reference: 7-Chloro-2-phenyl-quinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 7-Chloro-2-phenyl-quinoline(61687-26-1)
• EPA Substance Registry System: 7-Chloro-2-phenyl-quinoline(61687-26-1)

Safety Data

• Hazardous Substances Data: 61687-26-1(Hazardous Substances Data)

Usage

General Description

7-Chloro-2-phenyl-Quinoline is a chemical compound that belongs to the class of organic compounds known as quinolines and derivatives. Quinolines are compounds containing a quinoline moiety, a bicyclic heterocycle made up of a benzene ring fused to a pyridine ring. As an organic chemical, 7-Chloro-2-phenyl-Quinoline has a molar mass of 227.7 g/mol. 7-chloro-2-phenyl-Quinoline could potentially be used in various chemical reactions and synthesization processes; however, specific safety measures and handling precautions should be adopted as its effects on health and the environment are not fully known.

Upstream product

• 98-86-2 acetophenone 
• 104-55-2 3-phenyl-propenal 
• 108-42-9 3-chloro-aniline 
• 612-61-3 7-chloroquinoline 
• 58518-08-4 1,1,1-trifluoro-4-phenylbut-3-yn-2-one 
• 536-74-3 phenylacetylene 
• 59236-37-2 2-amino-4-chlorobenzaldehyde 
• 19433-17-1 acetophenone O-acetyloxime 
• 37585-16-3 (2-amino-4-chlorophenyl)methanol 
• 5551-11-1 4-Chloro-2-nitrobenzaldehyde 
• 6529-53-9 1-(2-bromoethyl)-4-chlorobenzene 
• 100-47-0 benzonitrile 
• 100-63-0 phenylhydrazine 
• 98-80-6 phenylboronic acid 

Downstream Products

• 1159987-42-4 (S)-7-chloro-2-phenyl-1,2,3,4-tetrahydroquinoline 
• 1613216-41-3 5,9-diphenyl-7-(2-phenylquinolin-7-yl)-7H-benzo[c]carbazole 
• 867164-54-3 2-phenyl-7-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-quinoline 

Relevant articles and documents

Visible-Light-Induced Amination of Quinoline at the C8 Position via a Postcoordinated Interligand-Coupling Strategy under Mild Conditions

The postcoordinated interligand-coupling strategy provides a useful and complementary protocol for synthesizing polydentate ligands. Herein, diastereoselective photoreactions of Λ-[Ir(pq)2(d-AA)] (Λ-d) and Λ-[Ir(pq)2(l-AA)] (Λ-l, where pq is 2-phenylquino

Ruthenium-catalyzed acceptorless dehydrogenative coupling of o-aminobenzyl alcohols with ketones to quinolines in the presence of carbonate salt

A ruthenium complex bearing a functional 2,2′-bibenzimidazole ligand [(p-cymene)Ru(BiBzImH2)Cl][Cl] was designed, synthesized and found to be a general and highly efficient catalyst for the synthesis of quinolines via acceptorless dehydrogenative coupling of o-aminobenzyl alcohols with ketones in the presence of carbonate salt. It was confirmed that NH units in the ligand are crucial for catalytic activity. The application of this catalytic system for the scale-gram synthesis of biologically active molecular was also undertaken. Notably, this research exhibits new potential of metal–ligand bifuctional catalysts for acceptorless dehydrogenative reactions.

Iron catalyzed metal-ligand cooperative approaches towards sustainable synthesis of quinolines and quinazolin-4(3H)-ones

Herein we report simple, efficient, and economically affordable metal-ligand cooperative strategies for synthesizing quinolines and quinazolin-4(3H)-ones via dehydrogenative functionalization of alcohols. Various polysubstituted quinolines and quinazolin-4(3H)-ones were prepared in good yields via dehydrogenative coupling of readily available alcohols with ketones and 2-aminobenzamides, respectively under air using a well-defined Fe(II)-catalyst, ([FeL1Cl2] (1)) bearing a redox-active azo-aromatic pincer 2-((4-chlorophenyl)diazenyl)-1,10-phenanthroline) (L1). Control experiments and mechanistic investigation disclose that the one-electron reduced mono-anionic species [1]? bearing an iron-stabilized azo-anion radical ligand catalyzes these reactions. Both iron and the redox-active arylazo ligand participate synergistically during the different steps of these catalytic reactions.