61750-20-7

Basic information

• Product Name: Morpholine, 4-[(4-methylphenyl)thioxomethyl]-
• Synonyms: 4-Methylthiobenzoesaeure-morpholid;4-methylthiobenzmorpholide;4-(4-methyl-thiobenzoyl)-morpholine;4-<(4-methylphenyl)methylsulfinyl>4-(Methyl)-thiobenzomorpholid;morpholino(p-tolyl)methanethione;HMS1585B10;(4-methylphenyl)(morpholin-4-yl)methanethione
• CAS NO: 61750-20-7
• Molecular Formula: C12H15NOS
• Molecular Weight: 221.323
• Mol File: 61750-20-7.mol
• Article Data: 19

Chemical Properties

• CAS DataBase Reference: Morpholine, 4-[(4-methylphenyl)thioxomethyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Morpholine, 4-[(4-methylphenyl)thioxomethyl]-(61750-20-7)
• EPA Substance Registry System: Morpholine, 4-[(4-methylphenyl)thioxomethyl]-(61750-20-7)

Safety Data

• Hazardous Substances Data: 61750-20-7(Hazardous Substances Data)

Upstream product

• 110-91-8 morpholine 
• 7559-36-6 4-methyl-β-nitrostyrene 
• 4394-85-8 4-morpholinecarboxaldehyde 
• 2789-88-0 1,2-bis(4-methylphenyl)acetylene 
• 766-97-2 4-n-methylphenylacetylene 
• 622-47-9 4-tolylacetic acid 
• 106-42-3 para-xylene 
• 104-87-0 4-methyl-benzaldehyde 
• 2362-77-8 (4-methylbenzylidene)phenylamine 
• 104-85-8 para-methylbenzonitrile 
• 53437-15-3 morpholine-4-sulfenyl chloride 
• 89980-67-6 p-methylbenzylmagnesium bromide 
• 162274-51-3 4-<(Diphenylphosphinoyl)(p-tolyl)methyl>morpholine 
• 3762-25-2 diethyl 4-methylbenzylphosphonate 

Downstream Products

• 2227-61-4 4-phenyl-2-(4′-methylphenyl)thiazole 
• 1264748-32-4 C₁₈H₂₂OS 
• 1314692-71-1 C₁₀H₁₀O₃S 
• 1314692-68-6 C₂₂H₁₈O₂S 
• 1310487-43-4 (Z)-S-2-(4-methylbenzylidene)-3-oxobutyl 4-methylbenzothioate 
• 85810-86-2 C₁₃H₁₈NOS⁽¹⁺⁾*I^(1-) 
• 99-94-5 p-Toluic acid 
• 122-00-9 para-methylacetophenone 
• 111097-40-6 4-(1-p-Tolyl-pentyl)-morpholine 
• 1671-77-8 n-butyl p-tolyl ketone 
• 134-84-9 4-Methylbenzophenone 

Relevant articles and documents

Metal-free three-component synthesis of thioamides from β-nitrostyrenes, amines and elemental sulfur

A metal-free C[dbnd]C bond cleavage reaction of β-nitrostyrenes in the presence of elemental sulfur and secondary amines/amides is described. Elemental sulfur serves as both a raw material and an oxidant for C[dbnd]C bond cleavage, and secondary amines or amides are both feasible nitrogen sources. Besides mild reaction condition and simple work-up procedure, the method provided thioamides with good to excellent yields.

Willgerodt-Kindler reaction at room temperature: Synthesis of thioamides from aromatic aldehydes and cyclic secondary amines

A simple method for the synthesis of thioamide derivatives in DMSO at room temperature and at 120 °C has been developed. Total 27 compounds were prepared under both conditions via a one-pot, three component reaction between substituted aromatic aldehydes,