618098-67-2 Usage
Chemical structure
The compound consists of a pyrazole ring attached to a 3-chlorophenyl group and a 4-methoxyphenyl group, with a carbonyl group present, making it an aldehyde.
Molecular weight
Approximately 296.7 g/mol
Functional groups
Pyrazole ring, chlorophenyl group, methoxyphenyl group, and aldehyde group.
Aromaticity
The compound contains two aromatic rings (phenyl and pyrazole), which contribute to its stability and reactivity.
Reactivity
The presence of the aldehyde group makes the compound susceptible to nucleophilic addition reactions, while the chlorophenyl group can undergo substitution reactions.
Solubility
The compound is likely to be soluble in organic solvents such as ethanol, methanol, and dichloromethane due to its nonpolar nature.
Melting point
The exact melting point is not provided, but it is expected to be relatively high due to the presence of aromatic rings and the planar structure of the molecule.
Boiling point
The exact boiling point is not provided, but it is expected to be relatively high due to the molecular size and the presence of aromatic rings.
Potential applications
The compound may have potential applications in organic synthesis, pharmaceuticals, or other industries due to its unique structure and reactivity.
Further research
Additional research and testing would be necessary to fully understand the properties and potential uses of this compound, as well as its stability, toxicity, and environmental impact.
Safety precautions
As with any chemical compound, appropriate safety measures should be taken when handling 1-(3-chlorophenyl)-3-(4-methoxyphenyl)-1H-pyrazole-4-carbaldehyde, including the use of gloves, eye protection, and a well-ventilated workspace.
Check Digit Verification of cas no
The CAS Registry Mumber 618098-67-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,1,8,0,9 and 8 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 618098-67:
(8*6)+(7*1)+(6*8)+(5*0)+(4*9)+(3*8)+(2*6)+(1*7)=182
182 % 10 = 2
So 618098-67-2 is a valid CAS Registry Number.
618098-67-2Relevant articles and documents
Synthesis and anti-inflammatory evaluation of new substituted 1-(3-chlorophenyl)-3-(4-methoxyphenyl)-1H-pyrazole derivatives
Fahmy, Hoda H.,Khalifa, Nagy M.,Nossier, Eman S.,Abdalla, Mohamed M.,Ismai, Magda M. F.
experimental part, p. 411 - 421 (2012/09/11)
A series of heterocyclic derivatives including 1,2,4-triazole-3(4H)-one (3a,b), 1H-pyrazol-5(4H)-one (4,5), 1H-pyrazol-4-carbonitrile (7), pyridine-3-carbonitrile (8, 9a,b), pyrimidine-5-carbonitrile (10a,b), methylpyrimidin-2(1H)-one or thione (11a,b), pyrimidine-5-carboxylate (12a,b), quinazolin-5(6H)-one (13a,b) and indeno [1,2-d] pyrimidin-5-one (14a,b) moieties conjugated with 1,3-disubstituted pyrazole moiety were synthesized on reaction with semicarbazide, thiosemicarbazide, 3-amino-5-oxo-2-pyrazoline, cyanoacetohydrazide, 2-acetyl thiophene, p-chloroacetophenone, urea, thiourea and 1,3-dicarbonyl compounds, respectively, by using 1-(3-chlorophenyl)-3-(4- methoxyphenyl)-1H-pyrazole-4-carboxaldehyde (2) as starting material. The structures of all the newly synthesized products have been established on the basis of analytical and spectral data. The anti-inflammatory screening showed that most of the obtained compounds were found to have significant anti-inflammatory activities with prostaglandin inhibition at a dose level of 2.5 and 5 mg/kg comparable to celecoxib as a reference control. The ulcer indices of all compounds are mainly in the safe level (UI = 2.10-4.27) except for compounds 9a and 14a, which were highly ulcerogenic.
