61892-54-4Relevant articles and documents
Identifying the important structural elements of brominated furanones for inhibiting biofilm formation by Escherichia coli
Han, Yongbin,Hou, Shuyu,Simon, Karen A.,Ren, Dacheng,Luk, Yan-Yeung
, p. 1006 - 1010 (2008)
A collection of structurally closely related furanones was synthesized to identify the most important structural elements in brominated furanones for inhibiting the formation of bacterial biofilms. The results suggest that a conjugated exocyclic vinyl bro
Synthesis of natural fimbrolides
Haval, Kishan P.,Argade, Narshinha P.
, p. 2198 - 2202 (2008/03/28)
Starting from citraconic anhydride, a three-step approach to fimbrolide congener is reported by taking the advantage of a regioselective Grignard reaction with an anhydride, followed by a dehydrative cyclization and double bromination-dehydrobromination s
A SHORT EFFICIENT SYNTHESIS OF 4-HYDROXY-5-(1-HYDROXYALKYL)-γ-BUTYROLACTONES
Scheeren, J.W.,Lange, J.
, p. 1609 - 1612 (2007/10/02)
The cycloaddition of α,β-epoxyaldehydes or ketones (2) with the ketene acetal MeHC=C(OMe)2 (1) gives epoxyoxetanes (3) in high yields.Without isolation they can be transformed into 4-hydroxy-5-(1-hydroxyalkyl)-γ-butyrolactones (6) via the epoxy esters 4 and trihydroxy esters (5).The lactones 6 appear to be valuable precursors for the synthesis of 5-(1-hydroxyalkyl)-3-methyl-2-5H-furanones (7) and 3-methyl-5-ylidene-2-5H-furanones (8)