620634-96-0Relevant articles and documents
Generating Skeletal Diversity and Complexity from Boron-Substituted 1,3-Dienes and Enophiles
Fran?ois, Benjamin,Eberlin, Ludovic,Berrée, Fabienne,Whiting, Andrew,Carboni, Bertrand
, p. 3282 - 3293 (2020)
Boron-substituted 1,3-dienes participate in ene reactions to afford new functionalized synthetic intermediates. After evaluating several enophiles as partners, the resulting products have been engaged in multistep sequences involving first a Diels Alder/allylboration process. A variety of skeletally diverse and complex polycyclic heterocycles were thus synthesized, such as tetrahydro-1H-isoindole-1,3(2H)-diones, eight-membered lactones or tricyclic spiro compounds.
Cobalt-Catalyzed Markovnikov-Type Selective Hydroboration of Terminal Alkynes
Chen, Jieping,Shen, Xuzhong,Lu, Zhan
supporting information, p. 690 - 694 (2020/11/30)
A cobalt-catalyzed Markovnikov-type hydroboration of terminal alkynes with HBpin to access α-alkenyl boronates with good regioselectivity and atom economy is reported. A new ligand has been developed for the cobalt hydride catalyst that has been used for a unique Markovnikov selective insertion of terminal alkynes into metal hydride bond. This operationally simple protocol exhibits excellent functional group tolerance to deliver valuable alkene derivatives.
Enol silyl ethers via copper(II)-catalyzed C-O bond formation
Chan, Daniel G.,Winternheimer, David J.,Merlic, Craig A.
supporting information; experimental part, p. 2778 - 2781 (2011/08/02)
Copper(II) acetate catalyzes the coupling of pinacol vinylboronates with silanols producing enol silyl ethers. This represents a novel enol silyl ether synthesis via formation of the C-O bond instead of the conventional Si-O bond. This also constitutes the first transition-metal-catalyzed oxidative cross-coupling with silanols.
