62123-80-2

Basic information

• Product Name: ETHYL 3-BROMOBENZOYL FORMATE
• Synonyms: ETHYL 3-BROMOBENZOYL FORMATE;ethyl 2-(3-bromophenyl)-2-oxoacetate;3-Bromo-oxo-benzeneacetic acid ethyl ester
• CAS NO: 62123-80-2
• Molecular Formula: C₁₀H₉BrO₃
• Molecular Weight: 257.08
• Mol File: 62123-80-2.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 323.6 °C at 760 mmHg
• Flash Point: 149.5 °C
• Appearance: /
• Density: 1.48 g/cm³
• Vapor Pressure: 0.00026mmHg at 25°C
• Refractive Index: 1.546
• Storage Temp.: 2-8°C
• CAS DataBase Reference: ETHYL 3-BROMOBENZOYL FORMATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 3-BROMOBENZOYL FORMATE(62123-80-2)
• EPA Substance Registry System: ETHYL 3-BROMOBENZOYL FORMATE(62123-80-2)

Safety Data

• Hazardous Substances Data: 62123-80-2(Hazardous Substances Data)

Usage

General Description

ETHYL 3-BROMOBENZOYL FORMATE is a chemical compound with the molecular formula C10H9BrO3. It is a colorless to yellow liquid with a fruity odor, commonly used as an intermediate in organic synthesis. ETHYL 3-BROMOBENZOYL FORMATE is commonly employed in the production of pharmaceuticals, agrochemicals, and advanced materials. It is also used as a reagent in chemical reactions and in the manufacture of other organic compounds. ETHYL 3-BROMOBENZOYL FORMATE is considered to be a hazardous chemical and should be handled and stored with caution due to its potential health and environmental effects.

InChI:InChI=1/C10H9BrO3/c1-2-14-10(13)9(12)7-4-3-5-8(11)6-7/h3-6H,2H2,1H3

Upstream product

• 108-36-1 1,3-dibromobenzene 
• 95-92-1 oxalic acid diethyl ester 
• 3132-99-8 m-bromobenzoic aldehyde 
• 64-17-5 ethanol 
• 67-66-3 chloroform 

Downstream Products

• 94163-56-1 Cyclohexyl-<3-brom-phenyl>-glykolsaeure-aethylester 

Relevant articles and documents

Tris(pentafluorophenyl)borane-Catalyzed Oxygen Insertion Reaction of α-Diazoesters (α-Diazoamides) with Dimethyl Sulfoxide

A tris(pentafluorophenyl)borane-catalyzed oxidation reaction of α-diazoesters (α-diazo amides) with dimethyl sulfoxide has been developed. The reaction proceeds under metal free conditions to afford a series α-ketoesters and α-ketoamides. The synthetic utility of this protocol is demonstrated through synthetic transformations and scaled-up synthesis. (Figure presented.).

CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE

Described herein are compounds, methods of making such compounds, pharmaceutical compositions and medicaments containing such compounds, and methods of using such compounds to treat or prevent diseases or disorders associated with the enzyme ceramide galactosyltransferase (CGT), such as, for example, lysosomal storage diseases. Examples of lysosomal storage diseases include, for example, Krabbe disease and Metachromatic Leukodystrophy.

DERIVATIVES OF 4-(2-AMINO-1-HYDROXYETHYL)PHENOL AS AGONISTS OF THE β2 ADRENERGIC RECEPTOR

The present invention provides a compound of formula (I) wherein: R1 is a group selected from -CH2OH, -NHC(O)H and R2 is a hydrogen atom; or R1 together with R2 form the group -NH-C(O)-CH=CH- wherein the nitrogen atom is bound to the carbon atom in the phenyl ring holding R1 and the carbon atom is bound to the carbon atom in the phenyl ring holding R2; R3 is selected from hydrogen and halogen atoms or groups selected from -SO-R5, -SO2- R5, -NH-CO-NH2, -CO-NH2, hydantoino, C1-4alkyl, C1-4alkoxy and -SO2NR5R6; R4 is selected from hydrogen atoms, halogen atoms and C1-4alkyl groups; R5 is a C1-4alkyl group or C3-8 cycloalkyl; R6 is independently selected from hydrogen atoms and C1-4alkyl groups; n, p and q are independently 0, 1 , 2, 3 or 4; m and s are independently 0, 1 , 2 or 3; r is 0, 1 or 2; with the provisos that: at least one of m and r is not 0; the sum n+m+p+q+r+s is 7, 8, 9, 10, 11 , 12 or 13; the sum q+r+s is 2, 3, 4, 5 or 6 or a pharmaceutically-acceptable salt, solvate or stereoisomer thereof.