62188-81-2

Basic information

• Product Name: methyl N-[(benzyloxy)carbonyl]alanylmethioninate
• CAS NO: 62188-81-2
• Molecular Formula: C₁₇H₂₄N₂O₅S
• Molecular Weight: 368.4479
• Mol File: 62188-81-2.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 583.5°C at 760 mmHg
• Flash Point: 306.7°C
• Density: 1.199g/cm³
• Vapor Pressure: 1.32E-13mmHg at 25°C
• Refractive Index: 1.538
• CAS DataBase Reference: methyl N-[(benzyloxy)carbonyl]alanylmethioninate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl N-[(benzyloxy)carbonyl]alanylmethioninate(62188-81-2)
• EPA Substance Registry System: methyl N-[(benzyloxy)carbonyl]alanylmethioninate(62188-81-2)

Safety Data

• Hazardous Substances Data: 62188-81-2(Hazardous Substances Data)

Upstream product

• 2491-18-1 (S)-methyl 2-amino-4-(methylthio)butanoate hydrochloride 
• 26607-52-3 Cbz-Ala-OH*DCHA 
• 10332-17-9 Met-OMe 
• 1142-20-7 N-Cbz-Ala 
• 501-53-1 benzyl chloroformate 
• 63-68-3 L-methionine 

Relevant articles and documents

KINETICS OF THE ALKALINE HYDROLYSIS OF SEVERAL N-BENZYLOXYCARBONYLDIPEPTIDE METHYL AND ETHYL ESTERS

The reaction rates of the alkaline hydrolysis of synthesized N-protected dipeptide methyl and ethyl esters were studied systematically.From the kinetic data the energies of activation, the pre-exponential factors and the reference values at 40 deg C were calculated.The rate of hydrolysis shows to be strongly dependent on the C-terminal amino acid in the sequence Gly >> Ala/Met/Phe > Leu >> Val/Pro.Surprisingly the N-terminal amino acid also exerts an effect, but in a different sequence.N-Terminal Phe in particular shows a relative accelerating effect.Remarkable is the significantly faster ester hydrolysis of glycine containing dipeptide ethyl esters in ethanol/water compared to the corresponding methyl esters in methanol/water.