622392-04-5

Basic information

• Product Name: 2-BROMO-5-IODOPYRAZINE
• Synonyms: 2-BROMO-5-IODOPYRAZINE;2-Bromo-5-iodopyrazine 98%;2-Bromo-5-iodopyrazine98%;2-Iodo-5-bromo pyrazine;Pyrazine,2-broMo-5-iodo-;2-Bromo-5-iodo-1,4-diazine
• CAS NO: 622392-04-5
• Molecular Formula: C₄H₂BrIN₂
• Molecular Weight: 284.88
• EINECS: 201-903-5
• Product Categories: Halides;Pyrazines, Pyrimidines & Pyridazines;API intermediates;Pyrazines, Pyrimidines & Pyridazines;Building Blocks;Pyrazine;Chemical Synthesis;Heterocyclic Building Blocks;New Products for Chemical Synthesis;Pyrazines
• Mol File: 622392-04-5.mol
• Article Data: 8

Chemical Properties

• Melting Point: 95-97°C
• Boiling Point: 273.708 °C at 760 mmHg
• Flash Point: 119.335 °C
• Appearance: /
• Density: 2.496 g/cm³
• Vapor Pressure: 0.009mmHg at 25°C
• Refractive Index: 1.678
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: -4.29±0.10(Predicted)
• CAS DataBase Reference: 2-BROMO-5-IODOPYRAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BROMO-5-IODOPYRAZINE(622392-04-5)
• EPA Substance Registry System: 2-BROMO-5-IODOPYRAZINE(622392-04-5)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26
• Hazardous Substances Data: 622392-04-5(Hazardous Substances Data)

Usage

General Description

2-Bromo-5-iodopyrazine, also known as 5-Bromo-2-iodopyrazine, is a chemical compound with the molecular formula C4H3BrIN2. It is a heterocyclic organic compound with a pyrazine ring, featuring both bromine and iodine substituents. This chemical is commonly used in pharmaceutical and agrochemical research as a building block for the synthesis of various biologically active compounds. It is also used as a reagent in organic synthesis and can be found in various chemical libraries for drug discovery purposes. 2-Bromo-5-iodopyrazine exhibits high reactivity due to the presence of both bromine and iodine atoms, making it a valuable component in the development of novel drugs and other chemical compounds.

InChI:InChI=1/C4H2BrIN2/c5-3-1-8-4(6)2-7-3/h1-2H

Upstream product

• 59489-71-3 5-amino-2-bromopyrazine 

Downstream Products

• 1352212-71-5 C₂₂H₂₄BrN₅O₂ 
• 1610927-93-9 2,5-bis((2-(4-(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)phenyl)-6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl)ethynyl)pyrazine 
• 1352212-67-9 methyl {(2S)-1-[(2S)-2-{4-[4-(5-bromopyrazin-2-yl)phenyl]-1H-imidazol-2-yl}pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl}carbamate 
• 1352212-71-5 tert-butyl (2S)-2-{4-[4-(5-bromopyrazin-2-yl)phenyl]-1H-imidazol-2-yl}pyrrolidine-1-carboxylate 
• 1338493-65-4 2-bromo-5-(phenylethynyl)pyrazine 
• 1196152-38-1 2-bromo-5-(trifluoromethyl)-pyrazine 
• 1093063-97-8 5'-iodo-3-methyl-3,4,5,6-tetrahydro-2H-[1,2']bipyrazinyl 
• 942624-06-8 2-iodo-5-methoxy-pyrazine 
• 649774-83-4 2-(5-bromo-2-pyrazinylethynyl)-5-(3,4,5-tridodecyloxyphenylethynyl)pyrazine 
• 649774-80-1 2-bromo-5-(3,4,5-tridodecyloxyphenylethynyl)pyrazine 

Relevant articles and documents

HYDROXY ISOXAZOLE COMPOUNDS USEFUL AS GPR120 AGONISTS

The present invention relates to a compound represented by formula (I) : and pharmaceutically acceptable salts thereof are disclosed as useful for treating or preventing diabetes, hyperlipidemia, obesity, NASH, inflammation related disorders, and related diseases and conditions. The compounds are useful as agonists of the G-protein coupled receptor GPR120. Pharmaceutical compositions and methods of treatment are also included.

HEPATITIS C VIRUS INHIBITORS

The present invention relates to compounds of the formula (I) and pharmaceutically acceptable salts thereof; to compositions containing such compounds; and to the of such compounds as inhibitors of HCV replication.

ORGANIC COMPOUNDS

The present invention provides heterocyclic derivatives that modulate the activity of stearoyl-CoA desaturase. Methods of using such derivatives to modulate the activity of stearoyl-CoA desaturase and pharmaceutical compositions comprising such derivatives are also encompassed.