622403-43-4

Basic information

• Product Name: 2-(4-Chloro-phenyliminomethyleneamino)-benzoic acid ethyl ester
• Synonyms: 2-(4-Chloro-phenyliminomethyleneamino)-benzoic acid ethyl ester
• CAS NO: 622403-43-4
• Molecular Weight: 300.744
• Mol File: 622403-43-4.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: 2-(4-Chloro-phenyliminomethyleneamino)-benzoic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-Chloro-phenyliminomethyleneamino)-benzoic acid ethyl ester(622403-43-4)
• EPA Substance Registry System: 2-(4-Chloro-phenyliminomethyleneamino)-benzoic acid ethyl ester(622403-43-4)

Safety Data

• Hazardous Substances Data: 622403-43-4(Hazardous Substances Data)

Upstream product

• 118-92-3 anthranilic acid 
• 2131-55-7 4-Chlorophenyl isothiocyanate 
• 179039-70-4 ethyl 2-(triphenylphosphoranylidene-amino)benzoate 
• 90408-05-2 o-azidobenzoic acid ethyl ester 
• 32045-49-1 ethyl-o-aminobenzoate hydrochloride 
• 31162-13-7 2-azidobenzoic acid 
• 104-12-1 p-chlorphenylisocyanate 

Downstream Products

• 1078626-36-4 C₃₄H₃₀Cl₂N₆O₄ 
• 1078626-09-1 3-(2-aminoethyl)-2-[4-chloroanilino]quinazolin-4(3H)-one 
• 1078626-30-8 C₃₀H₂₂Cl₂N₆O₂ 
• 1078626-12-6 C₁₇H₁₇ClN₄O 
• 1078626-33-1 C₃₁H₂₄Cl₂N₆O₂ 
• 1597437-89-2 (E)-3-[2-((4-chloro-3-nitrobenzylidene)amino)ethyl]-2-[(4-chlorophenyl)-amino]quinazolin-4(3H)-one 
• 1597437-90-5 (E)-3-[2-(benzylideneamino)ethyl]-2-[(4-chlorophenyl)amino]quinazolin-4(3H)-one 
• 1597437-91-6 (E)-2-[(4-chlorophenyl)amino]-3-[2-((3-nitrobenzylidene)amino)ethyl]quinazolin-4(3H)-one 
• 1597437-92-7 (E)-2-[(4-chlorophenyl)amino]-3-[2-((4-methoxybenzylidene)amino)ethyl]quinazolin-4(3H)-one 
• 1597437-93-8 (E)-2-[(4-chlorophenyl)amino]-3-[2-((3-hydroxy-4-methoxybenzylidene)amino)ethyl]quinazolin-4(3H)-one 
• 713096-90-3 2-butyl-3-(4-chlorophenyl)quinazolin-4(3H)-one 
• 1788-93-8 3-(4-chlorophenyl)-2-methyl-3H-quinazolin-4-one 
• 1189289-67-5 3-(4-chlorophenyl)-2-ethenylquinazolin-4(3H)-one 
• 1414871-31-0 3-(4-chlorophenyl)-2-cyclohexylquinazolin-4(3H)-one 

Relevant articles and documents

Tetrabutylammonium fluoride promoted intramolecular nucleophilic attack of an ester group on a carbodiimide: Preparation of 1,3-oxazolin-5-ones and 3,1-benzoxazin-4-ones

Functionalized carbodiimides bearing an ester group either at the α or β position undergo cyclization in the presence of tetrabutylammonium fluoride (TBAF) under mild conditions to give 1,3-oxazolin-5-ones or 3,1-benzoxazin-4-ones in synthetically useful yields.

Novel 4(3H)-Quinazolinone Derivatives Containing an Isoxazole Moiety: Design, Synthesis, and Bioactivity Evaluation

The aim of the present study is to design and synthesize a series of novel 4(3H)-quinazolinone derivatives containing an isoxazole moiety and evaluate their antifungal activity against Gibberella zeae (G. zeae), Fusarium oxysporum (F. oxysporum), Cytospor

Functionalized carbodiimide mediated synthesis of 2,3-disubstituted quinazolin-4(3 H)-ones via the tandem strategy of C-nucleophilic addition and intramolecular NH-substitution cyclization

A facile synthesis of quinazolin-4(3H)-ones possessing carbon substituents at positions 2 and 3 has been developed. Key to the synthesis is a tandem strategy involving introduction of a 2-substituent and construction of the quinazolinone framework via C-nucleophilic addition to the carbodiimide cumulenic carbon followed by intramolecular nucleophilic substitution by the newly formed NH moiety at the proximal ester group.