623565-57-1

Basic information

• Product Name: 4H-Pyrazolo[5,1-c][1,4]oxazine-2-carboxylic acid, 6,7-dihydro-, ethyl ester
• Synonyms: 4H-Pyrazolo[5,1-c][1,4]oxazine-2-carboxylic acid, 6,7-dihydro-, ethyl ester;6,7-Dihydro-4H-pyrazolo[5,1-c][1,4]oxazine-2-carboxylic acid ethyl ester;Ethyl 6,7-dihydro-4H-pyrazolo[5,1-c][1,4]oxazine-2-carboxylate;ethyl 4H,6H,7H-pyrazolo[3,2-c][1,4]oxazine-2-carboxylate
• CAS NO: 623565-57-1
• Molecular Formula: C₉H₁₂N₂O₃
• Molecular Weight: 196.20318
• Mol File: 623565-57-1.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 367.269 °C at 760 mmHg
• Flash Point: 175.918 °C
• Appearance: /
• Density: 1.35 g/cm³
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4H-Pyrazolo[5,1-c][1,4]oxazine-2-carboxylic acid, 6,7-dihydro-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4H-Pyrazolo[5,1-c][1,4]oxazine-2-carboxylic acid, 6,7-dihydro-, ethyl ester(623565-57-1)
• EPA Substance Registry System: 4H-Pyrazolo[5,1-c][1,4]oxazine-2-carboxylic acid, 6,7-dihydro-, ethyl ester(623565-57-1)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 623565-57-1(Hazardous Substances Data)

Usage

General Description

4H-Pyrazolo[5,1-c][1,4]oxazine-2-carboxylic acid, 6,7-dihydro-, ethyl ester is a chemical compound that belongs to the pyrazolo[5,1-c][1,4]oxazine class. It is an ethyl ester derivative of the dihydro form of the acid. 4H-Pyrazolo[5,1-c][1,4]oxazine-2-carboxylic acid, 6,7-dihydro-, ethyl ester has potential applications in the field of pharmacology and medicinal chemistry due to its structural features. It may have biological activity and could be used in the development of new drugs or as a research tool for studying biological processes. Further research is needed to fully understand its properties and potential uses in various fields.

Upstream product

• 623565-56-0 3-oxo-6,7-dihydro-3H-[1,2,3]oxadiazolo[4,3-c][1,4]oxazine-8(4H)ylium-3a-ide 
• 623-47-2 propynoic acid ethyl ester 

Downstream Products

• 623565-60-6 4-nitrobenzyl (5R)-6-[(acetyloxy)(6,7-dihydro-4H-pyrazolo[5,1-c][1,4]oxazin-2-yl)methyl]-6-bromo-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate 
• 623565-59-3 6,7-dihydro-4H-pyrazolo[5,1-c][1,4]oxazine-2-carbaldehyde 
• 623565-58-2 (6,7-dihydro-4H-pyrazolo[5,1-c][1,4]oxazin-2-yl)methanol 

Relevant articles and documents

Polyheterocyclic substituted pyrimidines or pyridylamine derivatives Composition and medical application thereof

The invention discloses a polycyclic substituted pyrimidine or pyridine amine derivative, and the structure is shown in a formula (I). The invention further discloses a pharmaceutically acceptable salt of the derivative, a solvate, a stereoisomer, a prodrug, a pharmaceutical composition and and an application thereof in medicine. The compounds of the present invention have significant adenosine A. 2A Receptor and/or adenosine A2B The receptor antagonism activity is very practical.

Bicyclic 6-alkylidene-penems as class-D beta-lactamases inhibitors

This invention relates to certain bicyclic 6-alkylidene penems which act as a inhibitor of class-D enzymes. β-Lactamases hydrolyze β-lactam antibiotics, and as such serve as the primary cause of bacterial resistance. The compounds of the present invention when combined with β-lactam antibiotics will provide an effective treatment against life threatening bacterial infections. In accordance with the present invention there are provided compounds of general formula I or a pharmaceutically acceptable salt or in vivo hydrolyzable ester R5 thereof: wherein: One of A and B denotes hydrogen and the other an optionally substituted fused bicyclic heteroaryl group; and X═O or S.

Process for preparing 6-alkylidene penem derivatives

The present invention provides a process of making compounds of formula I, which are useful for the treatment of bacterial infection or disease.