623942-84-7

Basic information

• Product Name: 3-Bromo-2-(hydroxymethyl)-6-methoxypyridine
• Synonyms: 3-Bromo-2-(hydroxymethyl)-6-methoxypyridine;(3-BroMo-6-Methoxypyridin-2-yl)Methanol
• CAS NO: 623942-84-7
• Molecular Formula: C₇H₈BrNO₂
• Molecular Weight: 218.049
• Mol File: 623942-84-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 282.658 °C at 760 mmHg
• Flash Point: 124.748 °C
• Appearance: /
• Density: 1.596 g/cm³
• Vapor Pressure: 0.002mmHg at 25°C
• Refractive Index: 1.575
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: 3-Bromo-2-(hydroxymethyl)-6-methoxypyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Bromo-2-(hydroxymethyl)-6-methoxypyridine(623942-84-7)
• EPA Substance Registry System: 3-Bromo-2-(hydroxymethyl)-6-methoxypyridine(623942-84-7)

Safety Data

• Hazardous Substances Data: 623942-84-7(Hazardous Substances Data)

Usage

General Description

3-Bromo-2-(hydroxymethyl)-6-methoxypyridine is a chemical compound with the molecular formula C7H8BrNO2. It is an organic compound with a pyridine ring substituted by a bromine atom, a hydroxymethyl group, and a methoxy group. This chemical is commonly used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. It can also be used in research and development for its unique properties and reactivity. Additionally, it may have potential applications in the pharmaceutical industry as a building block in the synthesis of biologically active compounds. Overall, 3-Bromo-2-(hydroxymethyl)-6-methoxypyridine is an important chemical compound with various potential uses across different industries.

InChI:InChI=1/C7H8BrNO2/c1-11-7-3-2-5(8)6(4-10)9-7/h2-3,10H,4H2,1H3

Upstream product

• 929000-66-8 3-bromo-6-chloropyridine-2-carboxylic acid 

Downstream Products

• 1057666-91-7 N-{1-[3,5-bis(trifluoromethyl)phenyl]ethyl}-N-({3-[(cyclopentylmethyl)(ethyl)amino]-6-methoxypyridin-2-yl}methyl)-5-[2-(methylsulfinyl)ethoxy]pyrimidin-2-amine 
• 1057666-92-8 N-{1-[3,5-bis(trifluoromethyl)phenyl]ethyl}-N-({3-[(cyclopentylmethyl)(ethyl)amino]-6-methoxypyridin-2-yl}methyl)-5-[2-(methylsulfonyl)ethoxy]pyrimidin-2-amine 
• 1057666-90-6 N-{1-[3,5-bis(trifluoromethyl)phenyl]ethyl}-N-({3-[(cyclopentylmethyl)(ethyl)amino]-6-methoxypyridin-2-yl}methyl)-5-[2-(methylthio)ethoxy]pyrimidin-2-amine 
• 156094-64-3 2-(bromomethyl)-3-bromo-6-methoxypyridine 
• 1301168-27-3 3-bromo-2-[4-[1-(2-fluoroethyl)-4-(4-pyridinyl)-1H-pyrazol-3-yl]phenoxymethyl]-6-methoxypyridine 
• 1006599-07-0 3-{1-[({3-[(cyclopentylmethyl)(ethyl)amino]-6-methoxypyridin-2-yl}methyl){5-[2-(methylsulfonyl)ethoxy]pyrimidin-2-yl}amino]methyl}-5-(trifluoromethyl)benzonitrile 
• 1006599-04-7 3-{1-[({3-[(cyclopentylmethyl)(ethyl)amino]-6-methoxypyridin-2-yl}methyl){5-[2-(methylthio)ethoxy]pyrimidin-2-yl}amino]methyl}-5-(trifluoromethyl)benzonitrile 
• 1270038-12-4 C₁₈H₂₁NO₅ 
• 1270038-13-5 C₁₈H₂₀ClNO₄ 
• 1270038-08-8 3-{3-[2-({(4S,5R)-5-[3,5-bis(trifluoromethyl)phenyl]-4-methyl-2-oxo-1,3-oxazolidin-3-yl}methyl)-6-methoxypyridin-3-yl]-4-methoxyphenyl}propanoic acid 
• 1270038-11-3 methyl 3-(3-[2-({(4S,5R)-5-[3,5-bis(trifluoromethyl)phenyl]-4-methyl-2-oxo-1,3-oxazolidin-3-yl}methyl)-6-methoxypyridin-3-yl]-4-methoxyphenyl)propanoate 
• 269058-53-9 6-[(3-bromo-6-methoxy-pyridin-2-yl)-hydroxy-methyl]-cyclohex-2-enone 
• 623942-64-3 2-[(3-bromo-6-methoxypyridin-2-yl)methyl]cyclohexanone 

Relevant articles and documents

SHP2 PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF

The present disclosure relates to novel compounds including formula (X) and pharmaceutical compositions thereof, and methods for inhibiting the activity of SHP2 phosphatase with the compounds and compositions of the disclosure. The present disclosure further relates to, but is not limited to, methods for treating disorders associated with SHP2 deregulation with the compounds and compositions of the disclosure.