624-19-1

Basic information

• Product Name: 4-bromoanilinium chloride
• Synonyms: 4-Bromoaniline HCL;4-bromoanilinium chloride
• CAS NO: 624-19-1
• Molecular Formula: C₆H₇BrN*Cl
• Molecular Weight: 208.48348
• EINECS: 210-835-4
• Mol File: 624-19-1.mol
• Article Data: 10

Chemical Properties

• Melting Point: 165.5 °C
• Appearance: /
• CAS DataBase Reference: 4-bromoanilinium chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 4-bromoanilinium chloride(624-19-1)
• EPA Substance Registry System: 4-bromoanilinium chloride(624-19-1)

Safety Data

• Hazardous Substances Data: 624-19-1(Hazardous Substances Data)

Usage

General Description

4-bromoanilinium chloride is a chemical compound consisting of a benzene ring with a bromine atom and an amino group attached to it, and a chloride ion. It is a salt that is commonly used as an intermediate in the synthesis of various organic compounds. It is also used as a catalyst in organic reactions and as a starting material for the production of pharmaceuticals, dyes, and other fine chemicals. The compound has a white crystalline appearance and is soluble in water, making it useful for a wide range of applications in organic chemistry. Additionally, 4-bromoanilinium chloride has been studied for its potential antimicrobial and anticancer properties, making it an interesting compound for further research and development.

InChI:InChI=1/C6H6BrN.ClH/c7-5-1-3-6(8)4-2-5;/h1-4H,8H2;1H

Upstream product

• 2617-78-9 N-(4-bromophenyl)formamide 
• 106-40-1 4-bromo-aniline 
• 103-88-8 4-bromoacetanilide 
• 586-78-7 para-nitrophenyl bromide 
• 97-00-7 1-chloro-2,4-dinitro-benzene 

Downstream Products

• 13631-76-0 (4-bromo-phenylhydrazono)-malonic acid diethyl ester 
• 120045-90-1 2-amino-6-(4-bromoanilino)purine 
• 106-37-6 1.4-dibromobenzene 
• 916151-04-7 1-(4-bromophenyl)-1H-1,2,3-triazole-4-carbaldehyde 
• 2028-85-5 (4-bromophenyl)diazonium chloride 
• 380360-51-0 5‐[(E)‐2‐(4‐bromophenyl)‐1‐diazenyl]‐2‐hydroxybenzoic acid 
• 2059-75-8 N,N'-bis(p-bromophenyl)thiourea 
• 2646-30-2 1-(4-bromophenyl)thiourea 
• 7510-78-3 2-((p-bromophenyl)amino)-2-phenylacetonitrile 
• 89393-95-3 1-(p-bromophenyl)-3-phenyl-5-(2-benzothiazolyl)formazan 
• 53015-88-6 1-(4-bromophenyl)-1,3,5-triazine-2,4,6(1H,3H,5H)-trione 
• 69695-13-2 1',3'-bis-(4-bromo-phenyl)-2,4'-dichloro-2λ⁵,4'λ⁵-dispiro[benzo[1,3,2]dioxaphosphole-2,2'-cyclodiphosphazane-4',2''-benzo[1,3,2]dioxaphosphole] 

Relevant articles and documents

Selective and Additive-Free Hydrogenation of Nitroarenes Mediated by a DMSO-Tagged Molecular Cobalt Corrole Catalyst

We report on the first cobalt corrole that effectively mediates the homogeneous hydrogenation of structurally diverse nitroarenes to afford the corresponding amines. The given catalyst is easily assembled prior to use from 4-tert-butylbenzaldehyde and pyrrole followed by metalation of the resulting corrole macrocycle with cobalt(II) acetate. The thus-prepared complex is self-contained in that the hydrogenation protocol is free from the requirement for adding any auxiliary reagent to elicit the catalytic activity of the applied metal complex. Moreover, a containment system is not required for the assembly of the hydrogenation reaction set-up as both the autoclave and the reaction vessels are readily charged under a regular laboratory atmosphere.

High graphite N content in nitrogen-doped graphene as an efficient metal-free catalyst for reduction of nitroarenes in water

Four kinds of nitrogen-doped graphene (NG) as metal-free catalysts are synthesized by a one-step hydrothermal reaction and thermal treatment using graphene oxide and urea as precursors. It is found that the reduction of nitroarenes can be catalyzed by using a low NG loading and a small amount of NaBH4 in water with high yield. The type of nitrogen species in NG has an important effect on the reduction reaction. The NG catalyst containing the most graphite N shows the highest catalytic activity during reduction of nitroarenes, which demonstrates that the graphite N of NG plays a key role in impelling this reaction. The reaction mechanism is proven by GC-MS experiments, and DFT calculations reveal the reasons for the graphite N showing better catalytic activity. It is worth noting that no dehalogenation phenomenon occurs during the reduction process for halogen-substituted nitroarenes in contrast to conventional metal catalysts. In addition, the NG catalyst can be simply recycled and efficiently used for eight consecutive runs with no significant decrease in activity.

A facile and efficient method for the selective deacylation of N-arylacetamides and 2-chloro-Narylacetamides catalyzed by SOCl2

Thionyl chloride efficiently and selectively promoted the deacylation of N-arylacetamides and 2-chloro-N-arylacetamides, under anhydrous conditions, without effecting the ester group, aminosulfonyl group, or benzyloxyamide group. This method, which has been successfully applied to a variety of substrates including different N-arylacetamides and 2-chloro-N-arylacetamides, has the attractive advantages of inexpensive reagents, satisfactory selectivity, excellent yields, short reaction time, and convenient workup. This new method can probably be used to selectively deacylate between aromatic amides and alkyl amides. Springer Science+Business Media B.V. 2011.