62416-02-8

Basic information

• Product Name: Benzene, 1-azido-2,3-dichloro-
• CAS NO: 62416-02-8
• Molecular Formula: C6H3Cl2N3
• Molecular Weight: 188.016
• Mol File: 62416-02-8.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: Benzene, 1-azido-2,3-dichloro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-azido-2,3-dichloro-(62416-02-8)
• EPA Substance Registry System: Benzene, 1-azido-2,3-dichloro-(62416-02-8)

Safety Data

• Hazardous Substances Data: 62416-02-8(Hazardous Substances Data)

Upstream product

• 608-27-5 2,3-dichloroaniline 
• 95-50-1 1,2-dichloro-benzene 
• 151169-74-3 2,3-dichlorobenzeneboronic acid 

Downstream Products

• 65245-78-5 C₁₃H₁₁Cl₂N₅ 
• 608-27-5 2,3-dichloroaniline 
• 519056-56-5 C₁₁H₉Cl₂N₃O 
• 1332502-23-4 5-(4-chlorophenyl)-2-{[1-(2,3-dichlorophenyl)-1H-1,2,3-triazol-4-yl]methyl}-4-[(2S)-3,3,3-trifluoro-2-hydroxypropyl]-2,4-dihydro-3H-1,2,4-triazol-3-one 
• 1443032-56-1 benzothiazol-2-yl-bis-{[1-(2,3-dichlorophenyl)-1H-[1,2,3]triazol-4-yl]methyl}amine 

Relevant articles and documents

Synthesis, Characterization, and Cytotoxic Evaluation of New Triazole Derivatives of Osthol

Abstract: Osthol [7-methoxy-8-(3-methylbut-2-en-1-yl)chromen-2-one] isolated fromPrangos pabularia was used as a startingmaterial for the synthesis of its various derivatives via modifications of thelactone ring. The resulting compounds were fully charact

ISOINDOLINE COMPOUND, AND PREPARATION METHOD, PHARMACEUTICAL COMPOSITION, AND APPLICATION OF ISOINDOLINE COMPOUND

The present invention relates to an isoindoline compound as represented by general formula (I) and used as a CRBN regulator, and a preparation method, a pharmaceutical composition, and an application of the isoindoline compound. Specifically, a class of polysubstituted isoindoline compound provided in the present invention, as a class of CRL4CRBN E3 ubiquitin ligase regulator having a novel structure, has good anti-tumor activity and immunoregulatory activity, and can be used for preparing drugs for treating diseases associated with a CRL4CRBN E3 ubiquitin ligase.

Site-Selective Copper-Catalyzed Amination and Azidation of Arenes and Heteroarenes via Deprotonative Zincation

Arene amination is achieved by site-selective C-H zincation followed by copper-catalyzed coupling with O-benzoylhydroxylamines under mild conditions. Key to this success is ortho-zincation mediated by lithium amidodiethylzincate base that is effective for a wide range of arenes, including nonactivated arenes bearing simple functionalities such as fluoride, chloride, ester, amide, ether, nitrile, and trifluoromethyl groups as well as heteroarenes including indole, thiophene, pyridine, and isoquinoline. An analogous C-H azidation is also accomplished using azidoiodinane for direct introduction of a useful azide group onto a broad scope of arenes and heteroarenes. These new transformations offer rapid access to valuable and diverse chemical space of aminoarenes. Their broad applications in organic synthesis and drug discovery are demonstrated in the synthesis of novel analogues of natural product (-)-nicotine and antidepressant sertraline by late-stage amination and azidation reactions.