624286-53-9

Basic information

• Product Name: Silane, trimethyl[[4-(phenylmethoxy)phenyl]methoxy]-
• CAS NO: 624286-53-9
• Molecular Formula: C17H22O2Si
• Molecular Weight: 286.446
• Mol File: 624286-53-9.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: Silane, trimethyl[[4-(phenylmethoxy)phenyl]methoxy]-(CAS DataBase Reference)
• NIST Chemistry Reference: Silane, trimethyl[[4-(phenylmethoxy)phenyl]methoxy]-(624286-53-9)
• EPA Substance Registry System: Silane, trimethyl[[4-(phenylmethoxy)phenyl]methoxy]-(624286-53-9)

Safety Data

• Hazardous Substances Data: 624286-53-9(Hazardous Substances Data)

Upstream product

• 836-43-1 4-benzyloxybenzyl alcohol 
• 999-97-3 1,1,1,3,3,3-hexamethyl-disilazane 
• 1058648-76-2 1-(benzyloxy)-4-((ethoxymethoxy)methyl) benzene 
• 392717-83-8 1-(benzyloxy)-4-((methoxymethoxy)methyl) benzene 

Downstream Products

• 4397-53-9 p-benzyloxybenzaldehyde 
• 836-43-1 4-benzyloxybenzyl alcohol 

Relevant articles and documents

An asymmetric Salamo-based Zn complex supported on Fe3O4MNPs: a novel heterogeneous nanocatalyst for the silyl protection and deprotection of alcohols under mild conditions

In this study, a magnetic asymmetric Salamo-based Zn complex (H2L = salen type di-Schiff bases)-supported on the surface of modified Fe3O4(Fe3O4@H2L-Zn) as a new catalyst was designed and characterizedvianumerous analytical techniques such as FT-IR spectroscopy, XRD, EDS, ICP-AES, SEM, TEM, TGA and VSM. An efficient and sustainable synthetic protocol has been presented for the synthesis of silyl ether substructuresviathe silyl protection of alcohols under mild conditions. The synthetic protocol involves a two-component solvent-free reaction between various hydroxyl-bearing substrates and hexamethyldisilazane (HMDS) as an inexpensive silylating agent using Fe3O4@H2L-Zn MNPs as a magnetically separable, recyclable and reusable heterogeneous catalyst. Fe3O4@H2L-Zn MNPs were also applied for the removal of silyl protecting groups from hydroxyl functions using water in CH2Cl2under green conditions. The catalyst demonstrated good to excellent catalytic yield efficiency for both the reactions compared to the commercial metal-based catalysts under green conditions for a wide range of substrates.

[InCl4]: An efficient catalyst-medium for alkoxymethylation of alcohols and their interconversion to acetates and TMS-ethers

A simple, green and chemoselective method for methoxymethylation and ethoxymethylation of primary and secondary alcohols using a Lewis acidic room temperature ionic liquid, [C4mim][InCl4], as catalyst and reaction medium under ambient temperature, microwave and ultrasonic irradiations is reported. In this catalytic system, the corresponding MOM-and EOM-ethers are obtained in excellent yields and in short reaction times. Furthermore, this catalytic system was used for mild and efficient transformations of these protected alcohols to their corresponding acetates and trimethylsilyl ethers under thermal conditions and microwave and ultrasonic irradiations.

Nanocrystalline TiO2 as an efficient and reusable catalyst for the chemoselective trimethylsilylation of primary and secondary alcohols and phenols

Nanocrystalline TiO2 was used as an efficient and recyclable catalyst for the chemoselective trimethylsilylation of primary and less hindered secondary alcohols and phenols with hexamethyldisilazane (HMDS). All reactions were performed under mild and completely heterogeneous conditions in good to excellent yields.