62438-03-3

Basic information

• Product Name: 5-METHYL-ISOXAZOLE-3-CARBOXYLIC ACID HYDRAZIDE
• Synonyms: CHEMBRDG-BB 3007474;ART-CHEM-BB B007474;5-METHYL-ISOXAZOLE-3-CARBOXYLIC ACID HYDRAZIDE;5-METHYLISOXAZOLE-3-CARBOHYDRAZIDE;AKOS B007474;SALOR-INT L482595-1EA;5-Methylisoxazole-3-carboxylicacidhydrazide,99%;3-Isoxazolecarboxylicacid,5-methyl-,hydrazide(7CI,9CI)
• CAS NO: 62438-03-3
• Molecular Formula: C₅H₇N₃O₂
• Molecular Weight: 141.13
• Product Categories: AMIDE;Heterocycles;Intermediates
• Mol File: 62438-03-3.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• Density: 1.291 g/cm³
• Refractive Index: 1.534
• Storage Temp.: 2-8°C
• Solubility: Dichloromethane, Methanol
• CAS DataBase Reference: 5-METHYL-ISOXAZOLE-3-CARBOXYLIC ACID HYDRAZIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-METHYL-ISOXAZOLE-3-CARBOXYLIC ACID HYDRAZIDE(62438-03-3)
• EPA Substance Registry System: 5-METHYL-ISOXAZOLE-3-CARBOXYLIC ACID HYDRAZIDE(62438-03-3)

Safety Data

• Hazard Codes: Xi
• Statements: R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
• Safety Statements: S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.; S36/37:Wear suitable p
• HazardClass: IRRITANT
• Hazardous Substances Data: 62438-03-3(Hazardous Substances Data)

Usage

Description

5-METHYL-ISOXAZOLE-3-CARBOXYLIC ACID HYDRAZIDE is an organic compound that serves as a key intermediate in the synthesis of GABAA receptor agonists, which are crucial in the development of antidepressant medications.
Used in Pharmaceutical Industry:
5-METHYL-ISOXAZOLE-3-CARBOXYLIC ACID HYDRAZIDE is used as an intermediate in the preparation of GABAA receptor agonists for their role in antidepressants. Its involvement in the synthesis of these agonists is vital, as they help regulate the GABA neurotransmitter system, which is integral to managing mood and anxiety disorders.

InChI:InChI=1/C5H7N3O2/c1-3-2-4(8-10-3)5(9)7-6/h2H,6H2,1H3,(H,7,9)

Upstream product

• 19788-35-3 methyl 5-methylisoxazole-3-carboxylate 
• 3209-72-1 ethyl 5-methylisoxazole-3-carboxylate 

Downstream Products

• 215874-89-8 6-chloro-3-(5-methylisoxazol-3-yl)-1,2,4-triazolo[3,4-a]phthalazine 
• 328-33-6 5-methyl-isoxazole-3-carboxylic acid N'-(4-dimethylamino-benzyl)-hydrazide 
• 101670-68-2 N-benzyl-N,N'-bis-(5-methyl-isoxazole-3-carbonyl)-hydrazine 
• 94373-20-3 5-methyl-isoxazole-3-carboxylic acid N'-(4-diethylamino-benzyl)-hydrazide 
• 92325-02-5 5-methyl-isoxazole-3-carboxylic acid N'-(2-dimethylamino-benzyl)-hydrazide 
• 93760-76-0 5-methyl-isoxazole-3-carboxylic acid N'-(3-dimethylamino-benzyl)-hydrazide 
• 91959-76-1 5-methyl-isoxazole-3-carboxylic acid N'-(4-methoxy-benzyl)-hydrazide 
• 92649-60-0 5-methyl-isoxazole-3-carboxylic acid N'-(4-isopropyl-benzyl)-hydrazide 
• 91396-23-5 5-methyl-isoxazole-3-carboxylic acid N'-(2-chloro-benzyl)-hydrazide 
• 69352-54-1 1-Furfuryl-2-<5-methyl-3-isoxazolyl-carbonyl)-hydrazin 
• 804435-88-9 1-n-Amyl-2-<5-Methyl-3-isoxazolylcarbonyl>-hydrazin 
• 805189-50-8 1-i-Amyl-2-<5-Methyl-3-isoxazolylcarbonyl>-hydrazin 
• 92673-52-4 1-Propyl-2-<5-Methyl-3-isoxazolylcarbonyl>-hydrazin 
• 90221-27-5 1-Aethyl-2-<5-Methyl-3-isoxazolylcarbonyl>-hydrazin 

Relevant articles and documents

Pyridine methylamino dithio formic acid heteroaryl naphthenic base ester compound and preparation method and application thereof

The invention relates to a compound as shown in a general formula (I) or pharmaceutically acceptable salts or solvates thereof, and relates to a preparation method of the compound and application thereof in preparing anti-tumor drugs. Please see the general formula (I) in the description.

Compounds Which Selectively Modulate The CB2 Receptor

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Pentaaza-cyclopental[a]naphthalene derivatives as ligands for GABAa α5 receptors

A class of 1,2,3a,4,x-pentaaza-cyclopenta[a]naphthalene compounds (x=6, 7, 8 or 9) is described. The compounds have a high affinity for the GABAAα5 receptors and show inverse agonist activity thereat. The compounds are useful in therapy where cognition enhancement is required.