62472-38-2Relevant articles and documents
Selective Phthalimido-N-oxyl (PINO)-Catalyzed C-H Cyanation of Adamantane Derivatives
Berndt, Jan-Philipp,Erb, Frederik R.,Ochmann, Lukas,Beppler, Jaqueline,Schreiner, Peter R.
supporting information, p. 493 - 498 (2019/02/26)
We present a new method for the selective C(sp 3)-H cyanation of adamantane derivatives with PINO as the hydrogen abstracting reagent. A cyano radical is thereby transferred from p - toluenesulfonyl cyanide, allowing the cyanation of adamantane derivatives in up to 71% yield. The protocol presents a novel way to orthogonally functionalized adamantanes that are otherwise difficult to prepare. Mechanistic studies support the hypothesis of a radical pathway.
Corresponding amine nitrile and method of manufacturing thereof
-
, (2017/10/22)
The invention relates to a preparation method of nitrile. Compared with the prior art, the preparation method has the characteristics of obvious reduction of the usage amount of ammonia sources, low environmental pressure, low energy consumption, low production cost, high purity and yields of nitrile products, and the like, and can be used for obtaining nitrile with a more complex structure. The invention also relates to a method for preparing corresponding amine with nitrile.
A facile and efficient one-pot synthesis of nitriles from carboxylic acids
Mlinari?-Majerski, Kata,Margeta, Renato,Veljkovi?, Jelena
, p. 2089 - 2091 (2007/10/03)
Direct transformation of aliphatic carboxylic acids to the corresponding nitriles can be easily performed with acetonitrile in the presence of sulfuric acid. Georg Thieme Verlag Stuttgart.