625115-91-5

Basic information

• Product Name: 1H-Indole-3-carbonitrile,6-amino-(9CI)
• Synonyms: 1H-Indole-3-carbonitrile,6-amino-(9CI)
• CAS NO: 625115-91-5
• Molecular Formula: C₉H₇N₃
• Molecular Weight: 157.175
• Product Categories: INDOLE
• Mol File: 625115-91-5.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• Density: 1.33
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: 1H-Indole-3-carbonitrile,6-amino-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole-3-carbonitrile,6-amino-(9CI)(625115-91-5)
• EPA Substance Registry System: 1H-Indole-3-carbonitrile,6-amino-(9CI)(625115-91-5)

Safety Data

• Hazardous Substances Data: 625115-91-5(Hazardous Substances Data)

Usage

General Description

1H-Indole-3-carbonitrile,6-amino-(9CI) is a chemical compound with the molecular formula C10H8N2. It is a derivative of indole, a heterocyclic aromatic compound commonly found in many natural products and pharmaceuticals. This particular compound contains a carbonitrile group and an amino group at the 6-position of the indole ring. It has potential applications in the pharmaceutical industry as a building block for the synthesis of various biologically active compounds. Additionally, its structural features make it of interest for research in medicinal chemistry and drug development. Moreover, the 1H-Indole-3-carbonitrile,6-amino-(9CI) compound may also have potential uses in agrochemicals and material sciences due to its unique chemical properties.

Upstream product

• 4769-96-4 6-nitroindole 
• 4769-99-7 6-nitro-1H-indole-3-carbonitrile 

Relevant articles and documents

Compositions for Treatment of Cystic Fibrosis and Other Chronic Diseases

The present invention relates to pharmaceutical compositions comprising an inhibitor of epithelial sodium channel activity in combination with at least one ABC Transporter modulator compound of Formula A, Formula B, Formula C, or Formula D. The invention also relates to pharmaceutical formulations thereof, and to methods of using such compositions in the treatment of CFTR mediated diseases, particularly cystic fibrosis using the pharmaceutical combination compositions.

COMPOSITIONS FOR TREATMENT OF CYSTIC FIBROSIS AND OTHER CHRONIC DISEASES

The present invention relates to pharmaceutical compositions comprising an inhibitor of epithelial sodium channel activity in combination with at least one ABC Transporter modulator compound of Formula A, Formula B, Formula C, or Formula D. The invention also relates to pharmaceutical formulations thereof, and to methods of using such compositions in the treatment of CFTR mediated diseases, particularly cystic fibrosis using the pharmaceutical combination compositions.

Novel indole inhibitors of IMPDH from fragments: Synthesis and initial structure-activity relationships

The elaboration of previously reported indole fragments as inhibitors of inosine monophosphate dehydrogenase (IMPDH) is described. The synthesis, in vitro inhibitory values for IMPDH II, PBMC proliferation and physicochemical properties are discussed.