625457-63-8Relevant articles and documents
Design and synthesis of novel chrysene-linked pyrrolo[2,1-c][1,4]-benzodiazepine hybrids as potential DNA-binding agents
Kamal, Ahmed,Ramesh,Ramulu,Srinivas,Rehana, Tasneem,Sheelu
, p. 3451 - 3454 (2003)
Chrysene-linked pyrrolobenzodiazepine hybrids have been prepared that posses cytotoxicity in some cancer cell lines. They also exhibit promising DNA-binding affinity and this is supported by molecular modeling studies.