62610-39-3

Basic information

• Product Name: 3,6-dichloro-2-methoxy-benzoic acid
• Synonyms: dicamba;Banvel;Mediben
• CAS NO: 62610-39-3
• Molecular Formula: C8H6Cl2O3
• Molecular Weight: 221.04
• Mol File: 62610-39-3.mol
• Article Data: 37

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3,6-dichloro-2-methoxy-benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3,6-dichloro-2-methoxy-benzoic acid(62610-39-3)
• EPA Substance Registry System: 3,6-dichloro-2-methoxy-benzoic acid(62610-39-3)

Safety Data

• Hazardous Substances Data: 62610-39-3(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 3401-80-7 3,6-dichloro-2-hydroxybenzoic acid 
• 583-78-8 2,5-dichlorophenol 
• 68938-81-8 potassium salt of 2,5-dichlorophenol 
• 50-79-3 2,5-dichlorobenzoic acid 
• 2905-69-3 methyl 2,5-dichlorobenzoate 
• 108-88-3 toluene 
• 95-46-5 2-methylphenyl bromide 
• 124-41-4 sodium methylate 
• 65-85-0 benzoic acid 
• 106-46-7 para-dichlorobenzene 
• 2200-85-3 5-bromo-3-chloro-2-hydroxybenzoic acid 
• 69-72-7 salicylic acid 
• 89-55-4 5-bromosalicyclic acid 

Downstream Products

• 1430102-88-7 dicamba phthalhydrazide diester 
• 1431852-91-3 C₈H₆Cl₂O₃*C₁₀H₁₀N₂ 
• 1354726-19-4 trimethyltetradecylammonium 3,6-dichloro-2-methoxybenzoate 
• 1918-00-9 3,6-dichloro-2-methoxybenzoate sodium salt 

Relevant articles and documents

Preparation methods of 3,6-dichloro-2-bromotoluene and dicamba

The invention provides a preparation method of dicamba. The preparation method comprises the following steps: S1) in the presence of a catalyst, 2-bromotoluene is subjected to a chlorination reactionin chlorosulfonic acid or concentrated sulfuric acid, and 3,6-dichloro-2-bromotoluene is obtained; S2), 3,6-dichloro-2-bromotoluene is subjected to an oxidation reaction and a methoxylation reaction in sequence, and dicamba is obtained. Compared with the prior art, 3,6-dichloro-2-bromotoluene is obtained from 2-bromotoluene after the directional chlorination reaction, and dicamba can be obtained by the oxidation reaction and the methoxylation reaction. The methods have the advantages of easily available raw materials, low comprehensive cost, high methoxylation reaction selectivity, high totalyield, stable product quality and simple process, and facilitate industrial implementation.

Selective removing method of benzene ring hydroxyl para-bromine and preparation method of dicamba

The invention provides a selective removing method of benzene ring hydroxyl para-bromine. The method comprises following steps: a compound represented as formula (I) in the description is subjected toa reaction under the alkaline condition and the action of metal powder to remove hydroxyl para-bromine ions, and a compound represented as formula (II) in the description is obtained. The benzene ring hydroxyl para-bromine ions are selectively removed under the alkaline condition and the action of the metal powder, the reaction has higher selectivity, conversion rate and reaction rate are high, and a prepared product has higher purity.

Preparation method of dicamba

The invention provides a preparation method of dicamba. The preparation method comprises the steps as follows: A) salicylic acid and bromine or hydrogen bromide are subjected to a reaction in concentrated sulfuric acid, 5-bromosalicylic acid is obtained; B) 5-bromosalicylic acid and chlorine are subjected to a chlorination reaction, 5-bromo-3,6-dichlorosalycylic acid is obtained; C) 5-bromo-3,6-dichlorosalycylic acid is subjected to a debromination reaction under the alkaline condition and under the action of metal powder, and 3,6-dichlorosalycylic acid is obtained; D) 3,6-dichlorosalycylic acid and halomethane are subjected to an etherification reaction in a mixed solvent of water and methanol, and methyl-3,6-dichloro-2-methoxybenzoate is obtained; E) methanol is removed by distillation;F) a system after distillation is left to stand for laying, an organic phase is distilled, and dicamba methyl ester is obtained; G) dicamba methyl ester is subjected to alkaline hydrolysis, acidification and drying, and dicamba is obtained. The route comprises few steps and has low difficulty, the equipment requirement and investment are lower, continuous production can be realized, no three wastes are produced, and the product yield and purity are higher.