62614-84-0

Basic information

• Product Name: 4-PIPERIDIN-4-YLPHENOL
• Synonyms: Phenol, 4-(4-piperidinyl)-
• CAS NO: 62614-84-0
• Molecular Formula: C₁₁H₁₅NO
• Molecular Weight: 177.24
• Mol File: 62614-84-0.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 322.229 °C at 760 mmHg
• Flash Point: 140.834 °C
• Appearance: /
• Density: 1.074 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.552
• Storage Temp.: 2-8°C(protect from light)
• PKA: 9.99±0.30(Predicted)
• CAS DataBase Reference: 4-PIPERIDIN-4-YLPHENOL(CAS DataBase Reference)
• NIST Chemistry Reference: 4-PIPERIDIN-4-YLPHENOL(62614-84-0)
• EPA Substance Registry System: 4-PIPERIDIN-4-YLPHENOL(62614-84-0)

Safety Data

• Hazardous Substances Data: 62614-84-0(Hazardous Substances Data)

Usage

Uses

4-(4-Piperidinyl)phenol, is a building block used in various chemical synthesis.

InChI:InChI=1/C11H15NO/c13-11-3-1-9(2-4-11)10-5-7-12-8-6-10/h1-4,10,12-13H,5-8H2

Upstream product

• 19099-93-5 benzyl 4-oxo-1-piperidinecarboxylate 
• 286961-24-8 benzyl 1,2,3,6-tetrahydro-4-(trifluoromethylsulphonyloxy)-pyridine-1-carboxylate 
• 203661-82-9 benzyl 4-(4-hydroxyphenyl)piperidine-1-carboxylate 
• 303975-71-5 tert-butyl 4-(4-methoxyphenyl)piperidine-1-carboxylate 
• 142001-83-0 1-benzyl-4-(4-benzyloxyphenyl)-4-hydroxypiperidine 
• 6793-92-6 p-benzyloxyphenylbromide 
• 3612-20-2 1-phenylmethyl-4-piperidone 
• 6748-48-7 4-(4-methoxyphenyl)-piperidinehydrochloride 
• 326812-69-5 4-(1-benzyl-piperidin-4-yl)-phenol 
• 1166820-03-6 benzyl 4-(4-hydroxyphenyl)-5,6-dihydropyridine-1(2H)-carboxylate 
• 171056-33-0 C₂₅H₂₅NO 

Downstream Products

• 1166820-04-7 4-(1-(3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)piperidin-4-yl)phenol 
• 1869912-48-0 4-(piperidine-4-yl)phenol hydrobromide 
• 1869912-40-2 (R)-4-(2-(4-(1-(3-methoxy-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)piperidin-4-yl)phenoxy)ethyl)-1,3-dimethylpiperazin-2-one: 6-hydroxy-2-naphthoic acid(1:1) co-crystal 
• 203661-82-9 benzyl 4-(4-hydroxyphenyl)piperidine-1-carboxylate 
• 149377-19-5 4-(4-hydroxy-phenyl)-piperidine-1-carboxylic acid tert-butyl ester 
• 1869912-39-9 (3R)?4-[2-[4-[1-(3-methoxy-[1,2,4]triazolo[4,3?b]pyridazin-6-yl)-4-piperidyl]phenoxy]ethyl]-1,3-dimethyl-piperazin-2-one 

Relevant articles and documents

[1,2,4]TRIAZOLO[4,3-B]PYRIDAZINES FOR USE IN THE TREATMENT OF PROLIFERATIVE DISEASES

The invention concerns compounds of Formula (I) (Formula (I)) or pharmaceutically-acceptable salts thereof, wherein R1, R2 and n have any of the meanings defined herein before in the description; processes for their preparation, pharmaceutical compositions containing them and their use as anti-proliferative and/or cell-killing agents.

[1,2,4] TRIAZOLO [4,3-B] PYRIDAZINES AS LIGANDS OF THE ANDROGEN RECEPTOR

The invention concerns bicyclic compounds of Formula (I): wherein, R1, R2, R3, R4, R5, X1, X2, Y, k, m, n and p are as defined in the description. The present invention also relates to processes for the preparation of such compounds, pharmaceutical compositions containing them and their use in the treatment of androgen- receptor associated conditions, particularly prostate cancer.

2-CYANOPYRROLOPYRIMIDINES AND PHARMACEUTICAL USES THEREOF

The invention relates to pyrrolo pyrimidines of formula (I), wherein Y represents -(CH2)t-O- or -(CH2)r-S-, p is 1 or 2, r is 1, 2 or 3, t is 1, 2 or 3, or Y is -(CH2)j- or -CH=CH-, j is 1 or 2; p is 1 or 2, or Y is -(CH2)f-, f is 1 or 2, p is 1, and the further radicals and symbols have the meaning as defined herein; their preparation, their use as pharmaceuticals, pharmaceutical compositions containing them, the use of such a compound for the manufacture of a pharmaceutical preparation for the treatment of neuropathic pain and to a method for the treatment of such a disease in animals, especially in humans.