62615-63-8

Basic information

• Product Name: 4,6,7-Trimethoxy-5-methylcoumarin
• Synonyms: 4,6,7-Trimethoxy-5-methylcoumarin;4,6,7-TriMethoxy-5-Methyl-2H-chroMen-2-one
• CAS NO: 62615-63-8
• Molecular Formula: C₁₃H₁₄O₅
• Molecular Weight: 250
• Mol File: 62615-63-8.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4,6,7-Trimethoxy-5-methylcoumarin(CAS DataBase Reference)
• NIST Chemistry Reference: 4,6,7-Trimethoxy-5-methylcoumarin(62615-63-8)
• EPA Substance Registry System: 4,6,7-Trimethoxy-5-methylcoumarin(62615-63-8)

Safety Data

• Hazardous Substances Data: 62615-63-8(Hazardous Substances Data)

Usage

General Description

4,6,7-Trimethoxy-5-methylcoumarin is a chemical compound with the molecular formula C13H14O5. It is a type of coumarin, a natural benzopyrone derivative found in a variety of plants, and is known for its pleasant aroma and potential medicinal properties. This specific compound has three methoxy groups and one methyl group attached to the coumarin core, giving it unique chemical and biological properties. It has been studied for its potential as an antioxidant, anti-inflammatory, and antimicrobial agent. Additionally, it has been investigated for its potential role in cancer therapy and as a neuroprotective compound. Its unique chemical structure and potential biological activities make 4,6,7-Trimethoxy-5-methylcoumarin an interesting target for further research and development of therapeutic applications.

Upstream product

• 186581-53-3 diazomethane 

Relevant articles and documents

SYNTHESIS OF COUMARSABIN AND 4,6,7-TRIMETHOXY-5-METHYL-2H-1-BENZOPYRAN-2-ONE

The condensation of orcinol with methylmalonic acid affords 4,7-dihydroxy-3,5-dimethyl-2H-1-benzopyran-2-one, 4, and 4,5-dihydroxy-3,7-dimethyl-2H-1-benzopyran-2-one, 5.Diazomethane methylation of 4 yields coumarsabin, 1, and 2,7-dimethoxy-3,5-dimethyl-4H-1-benzopyran-4-one, 8.Methylation of 5 gives the coumarin 6 and the chromone 7. 4,6,7-Trimethoxy-5-methyl-2H-1-benzopyran-2-one, 2, a naturally occurring coumarin, has been synthesized from 4,7-dimethoxy-5-methyl-2H-1-benzopyran-2-one (siderin), 3.Alkaline persulphate oxidation of 3 gives 2,5-dihydroxy-4-methoxy-6-methylacetophenone, 9, and 4,6-dihydroxy-5-methyl-7-methoxy-2H-1-benzopyran-2-one, 11, which on methylation with diazomethane gives 2.