626606-17-5

Basic information

• Product Name: 2-(2-chlorophenyl)-4-methyl-1H-benzimidazole
• Synonyms: 2-(2-chlorophenyl)-4-methyl-1H-benzimidazole
• CAS NO: 626606-17-5
• Molecular Weight: 242.708
• Mol File: 626606-17-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-(2-chlorophenyl)-4-methyl-1H-benzimidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-chlorophenyl)-4-methyl-1H-benzimidazole(626606-17-5)
• EPA Substance Registry System: 2-(2-chlorophenyl)-4-methyl-1H-benzimidazole(626606-17-5)

Safety Data

• Hazardous Substances Data: 626606-17-5(Hazardous Substances Data)

Upstream product

• 609-65-4 o-chlorobenzoyl chloride 
• 2687-25-4 3-methyl-1,2-benzenediamine 
• 118-91-2 ortho-chlorobenzoic acid 

Downstream Products

• 626606-12-0 1-[2-(2-chlorophenyl)-4-methylbenzimidazol-1-yl]propan-2-ol 

Relevant articles and documents

Water-mediated synthesis of 2-substituted benzimidazoles by boric acid and glycerol

A very simple, mild, and highly efficient green catalyst has been developed for the synthesis of 2-substituted benzimidazoles by treatment of substituted ortho-phenylenediamines and aldehydes in water at 80C in the presence of boric acid (5 mol-%) and glycerol (0.05 mL). This methodology has been standardized on 55 substrates, and nine new compounds have been synthesized.

Intramolecular Aromatic Nucleophilic Substitution of the Benzimidazole-Activated Nitro Group

(Equation Presented) A wide range of 2-(2-nitrophenyl)-1H-benzimidazoles undergo high-yielding intramolecular SNAr of nitrite with N-pendant alkoxides under mild conditions (DMF, rt). When this operationally simple process is carried out at ele