6270-06-0 Usage
Chemical Properties
White Solid
Uses
N-(2-Chloroethyl)phthalimide may be used in the preparation of 1-[(dialkylamino)alkyl]-1,8-napthyridin-2(1H)ones and were evaluated for the inhibition of gastric acid secretion invivo.
General Description
N-(2-Chloroethyl)phthalimide can be prepared by the reaction of potassium phthalimide and 2-chloroethyl tosylate.
Check Digit Verification of cas no
The CAS Registry Mumber 6270-06-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,2,7 and 0 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 6270-06:
(6*6)+(5*2)+(4*7)+(3*0)+(2*0)+(1*6)=80
80 % 10 = 0
So 6270-06-0 is a valid CAS Registry Number.
InChI:InChI=1/C10H8ClNO2/c11-5-6-12-9(13)7-3-1-2-4-8(7)10(12)14/h1-4H,5-6H2
6270-06-0Relevant articles and documents
Nucleophilic Substitutions of Alcohols in High Levels of Catalytic Efficiency
Stach, Tanja,Dr?ger, Julia,Huy, Peter H.
supporting information, p. 2980 - 2983 (2018/05/28)
A practical method for the nucleophilic substitution (SN) of alcohols furnishing alkyl chlorides, bromides, and iodides under stereochemical inversion in high catalytic efficacy is introduced. The fusion of diethylcyclopropenone as a simple Lewis base organocatalyst and benzoyl chloride as a reagent allows notable turnover numbers up to 100. Moreover, the use of plain acetyl chloride as a stoichiometric promotor in an invertive SN-type transformation is demonstrated for the first time. The operationally straightforward protocol exhibits high levels of stereoselectivity and scalability and tolerates a variety of functional groups.