627099-18-7Relevant articles and documents
Synthesis of 3-Aminochroman Derivatives by Radical Cyclization
Pave, Gregoire,Usse-Versluys, Stephanie,Viaud-Massuard, Marie-Claude,Guillaumet, Gerald
, p. 4253 - 4256 (2007/10/03)
(Equation presented) Enantiomerically pure 5-acetyl-3-amino-3,4-dihydro-2H- 1-benzopyran and methyl 3-amino-3,4-dihydro-2H-1-benzopyran-5-carboxylate were successfully synthesized starting from D- or L-serine. The formation of the benzopyran ring involved a radical cyclization step. The enantiomeric purities of the final aminochroman derivatives were determined by capillary electrophoresis using β-cyclodextrins as a chiral selector.