6274-57-3Relevant articles and documents
Living photolytic ring-opening polymerization of amino-functionalized [1]ferrocenophanes: Synthesis and layer-by-layer self-assembly of well-defined water-soluble polyferrocenylsilane polyelectrolytes
Wang, Zhuo,Masson, Georgeta,Peiris, Frank C.,Ozin, Geoffrey A.,Manners, Ian
, p. 9372 - 9383 (2007)
Facile synthetic routes have been developed that provide access to cationic and anionic water-soluble polyferrocenylsilane (PFS) polyelectrolytes with controlled molecular weight and narrow polydispersity. Living photolytic ring-opening polymerization of
Heterogeneous Catalyzed Chemoselective Reductive Amination of Halogenated Aromatic Aldehydes
Dumoleijn, Kim N. R.,Villa, Alberto,Marelli, Marcello,Prati, Laura,Moonen, Kristof,Stevens, Christian V.
, p. 3021 - 3026 (2021/05/18)
The chemoselective conversion of a specific functional group in a multifunctional substrate is of great importance in the chemical industry to obtain cost efficient, sustainable and waste free processes. This work focuses on the chemoselective amination of halogenated aromatic aldehydes with dimethyl amine towards halogenated aromatic amines, a raw material used in the production of for example agrochemical active ingredients. It was found that by combining palladium, a metal known for dehalogenation reactions, and copper, known for its direct hydrogenation of aldehydes to alcohols, in one heterogeneous bimetallic catalyst, a synergistic effect is obtained. By depositing copper onto a palladium on carbon catalyst with a Cu/Pd ratio of at least 1 : 1, the yield could be increased from 66 % (Pd/C) to 98 % (PdCu/C). Moreover, this highly active and stable catalyst also showed suppressed dehalogenation side-reactions in several other chemical conversions such as hydrogenation of nitro functional groups and hydrogenation of aldehydes.
SUBSTITUTED IMIDAZOLE CARBOXAMIDES AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS
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Paragraph 00325, (2021/04/01)
The invention provides substituted imidazole carboxamides and related compounds, compositions containing such compounds, medical kits, and methods for using such compounds and compositions to treat a medical disorder, e.g., cancer, lysosomal storage disorder, neurodegenerative disorder, inflammatory disorder, in a patient.