62764-72-1Relevant articles and documents
Intermolecular C-H Amidation of Alkenes with Carbon Monoxide and Azides via Tandem Palladium Catalysis
Gu, Zheng-Yang,Wu, Yang,Jin, Feng,Bao, Xiaoguang,Xia, Ji-Bao
, p. 3361 - 3371 (2021/04/09)
An atom- and step-economic intermolecular multi-component palladium-catalyzed C-H amidation of alkenes with carbon monoxide and organic azides has been developed for the synthesis of alkenyl amides. The reaction proceeds efficiently without an ortho -directing group on the alkene substrates. Nontoxic dinitrogen is generated as the sole by-product. Computational studies and control experiments have revealed that the reaction takes place via an unexpected mechanism by tandem palladium catalysis.
Novel method for synthesizing sulfonyl ketoamide
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Paragraph 0024-0030; 0071-0078, (2020/06/09)
The invention discloses a novel method for synthesizing sulfonyl ketoamide, which comprises the following steps: adding a 1,3-dicarbonyl compound, organic azide, a catalyst and a solvent, and introducing CO to react; removing the solvent under reduced pressure; and carrying out column chromatography by using an eluting agent to obtain a sulfonyl ketoamide derivative. In the process of synthesizingthe sulfonyl ketoamide derivative, various 1,3-dicarbonyl compounds, CO and sulfonyl azide are used as raw materials, the organic azide is used for replacing unstable isocyanate, the reaction substrate range is greatly enlarged, the raw materials are simple and easy to obtain, reaction conditions are mild, the method is environmentally friendly, no additive is needed, and the yield is high.
N -Sulfonyl acetylketenimine as a highly reactive intermediate for the synthesis of N -sulfonyl amidines
Yang, Weiguang,Huang, Dayun,Zeng, Xiaobao,Luo, Dongping,Wang, Xinyan,Hu, Yuefei
, p. 8222 - 8225 (2018/07/29)
A highly reactive intermediate N-sulfonyl acetylketenimine was generated from a 3-butyn-2-one participating CuAAC/ring-opening method. Its high reactivity due to bearing two EWGs allowed us to offer the first example of a reaction between ketenimine and amide to synthesize N-sulfonyl amidines efficiently.