62773-09-5

Basic information

• Product Name: 7-CHLOROMETHYL-THIAZOLO[3,2-A]PYRIMIDIN-5-ONE
• Synonyms: 7-(Chloromethyl)-5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one;7-(chloromethyl)-5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one(SALTDATA: FREE);7-(chloromethyl)-5H-thiazolo[3,2-a]pyrimidin-5-one;7-Chloromethyl-thiazolo[3,2-α]pyrimidin-5-one≥ 99% (HPLC)
• CAS NO: 62773-09-5
• Molecular Formula: C₇H₅ClN₂OS
• Molecular Weight: 200.64
• Mol File: 62773-09-5.mol
• Article Data: 5

Chemical Properties

• Melting Point: 133 °C(Solv: ethanol (64-17-5))
• Boiling Point: 328.1 °C at 760 mmHg
• Flash Point: 152.2 °C
• Appearance: /
• Density: 1.6 g/cm³
• Vapor Pressure: 0.000194mmHg at 25°C
• Refractive Index: 1.733
• PKA: -0.07±0.70(Predicted)
• CAS DataBase Reference: 7-CHLOROMETHYL-THIAZOLO[3,2-A]PYRIMIDIN-5-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 7-CHLOROMETHYL-THIAZOLO[3,2-A]PYRIMIDIN-5-ONE(62773-09-5)
• EPA Substance Registry System: 7-CHLOROMETHYL-THIAZOLO[3,2-A]PYRIMIDIN-5-ONE(62773-09-5)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 62773-09-5(Hazardous Substances Data)

Usage

Chemical Properties

White to off-white crystals

InChI:InChI=1/C7H5ClN2OS/c8-4-5-3-6(11)10-1-2-12-7(10)9-5/h1-3H,4H2

Upstream product

• 96-50-4 2-thiazolylamine 
• 638-07-3 ethyl (2-chloroaceto)acetate 

Relevant articles and documents

An efficient synthesis of new thiazolopyrimidinones under microwave irradiation

7-Chloromethyl-6-nitro-5H-thiazolo[3,2-a]pyrimidin-5-one (2) is obtained by cyclocondensation of 2-aminothiazole with ethyl 4-chloroacetoacetate. This product was shown to react with various nitronate or malonate anions under microwave irradiation to give

Substituted pyrimidinyl organophosphorus insecticides

An organophosphorus compound having the structural formula STR1 where R is C1 -C4 alkyl; R1 is hydrogen or methyl; or R and R1 together are a diradical having the formula --SC(Y)=Z--, where Y is halogen, hydrogen or C1 -C2 alkyl; and Z is nitrogen, CH, C(CH3) or C(C2 H5) with the proviso that if Y is hydrogen, Z cannot be CH; R2 is hydrogen, chlorine or bromine; R3 is methyl or ethyl; R4 is methoxy, ethoxy, --SCH3 or --SC2 H5 ; and X is oxygen or sulfur and their hydrochlorides is disclosed. These compounds are useful as insecticides or nematocides. In another aspect of this invention a method of controlling rice planthoppers is provided. In this method an insecticidally effective amount of a compound having the formula given above where R is C1 -C4 alkyl or benzyl; R1 is hydrogen or C1 -C3 alkyl; or R and R1 together are a diradical selected from the group consisting of --CH=CH--CH=CH--, --CH=CCl--CH=CH--, --CH=C(CH3)--CH=CH-- and --SC(Y)=Z--, where Y is halogen, hydrogen or C1 -C2 alkyl; and Z is nitrogen, CH, C(CH3) or C(C2 H5); R2 is hydrogen or bromine; R3 is methyl or ethyl; R4 is methoxy, ethoxy or propylthio, with the proviso that if R2 is bromine, R4 is propylthio, and X is oxygen or sulfur is applied to the loci where rice planthoppers reside.

β Substituted enamines, XI. Condensation products from reactions of γ chloroacetoacetic ester with primary aromatic and heteroaromatic amines

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